Rabbit MettL7B Polyclonal Antibody | anti-METTL7B antibody

MettL7B Antibody

Cat. Num. AAA150127

• Gene Names: METTL7B; ALDI
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: MettL7B Antibody is affinity chromatography purified via peptide column.
• Synonyms: MettL7B; Polyclonal Antibody; MettL7B Antibody; ALDI; Methyltransferase-like protein 7B; methyltransferase like 7B; anti-METTL7B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This MettL7B antibody is predicted to not cross-react with MettL7A.
• Purity/Purification: MettL7B Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 244

• Applicable Applications for anti-METTL7B antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: MettL7B antibody can be used for detection of Mettl7B by Western blot at 2 - 4 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL.
• Conjugate: Unconjugated
• Immunogen: MettL7B antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human MettL7B.
• Buffer: MettL7B Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: MettL7B antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of MettL7B in rat spleen tissue lysate with MettL7B antibody at (A) 2 and (B) 4 μg/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of Mett7LB in human spleen tissue with MettL7B antibody at 2.5 μg/mL.)

Related Product Information for anti-METTL7B antibody

MettL7B Antibody: MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

NCBI and Uniprot Product Information

• NCBI GI #: 164663805
• NCBI GeneID: 196410
• NCBI Accession #: NP_689850
• NCBI GenBank Nucleotide #: NM_152637.2
• UniProt Accession #: Q6UX53; Q8WUI1; A8K247
• Molecular Weight: 27,775 Da
• NCBI Official Full Name: methyltransferase-like protein 7B
• NCBI Official Synonym Full Names: methyltransferase like 7B
• NCBI Official Symbol: METTL7B
• NCBI Official Synonym Symbols: ALDI
• NCBI Protein Information: methyltransferase-like protein 7B; associated with lipid droplets 1
• UniProt Protein Name: Methyltransferase-like protein 7B
• Protein Family: Methyltransferase-like protein
• UniProt Gene Name: METTL7B
• UniProt Entry Name: MET7B_HUMAN

Uniprot Description

METTL7B: Probable methyltransferase. Belongs to the methyltransferase superfamily.

Protein type: Methyltransferase, protein arginine, predicted; Methyltransferase; EC 2.1.1.-; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: cytoplasm

Molecular Function: S-adenosylmethionine-dependent methyltransferase activity

Biological Process: methylation