Western Blot (WB)
(Western blot analysis of lysates from U-87 MG, THP-1, A431 cell line, human testis, mouse heart, mouse cerebellum tissue lysate(from left to right), using MESP1 Antibody (Mouse). A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Rabbit Mesp1 Polyclonal Antibody | anti-Mesp1 antibody
Mouse Mesp1 Antibody (Center)
Western Blot (WB)
(Western blot analysis of lysates from U-87 MG, THP-1, A431 cell line, human testis, mouse heart, mouse cerebellum tissue lysate(from left to right), using MESP1 Antibody (Mouse). A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from U-87 MG, THP-1, A431 cell line, human testis, mouse heart, mouse cerebellum tissue lysate(from left to right), using MESP1 Antibody (Mouse). A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Western Blot (WB)
(Mouse Mesp1 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the MESP1 antibody detected the MESP1 protein (arrow).)
Western Blot (WB)
(Mouse Mesp1 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the MESP1 antibody detected the MESP1 protein (arrow).)
Li, P., et al. Dev. Cell 18(3):480-485(2010)
Powers, S.E., et al. Development 137(2):249-259(2010)
Randall, V., et al. J. Clin. Invest. 119(11):3301-3310(2009)
Dominguez-Frutos, E., et al. Mech. Dev. 126(10):873-881(2009)
NCBI and Uniprot Product Information
Uniprot Description
MESP1: Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.
Protein type: Transcription factor; Cell development/differentiation
Cellular Component: nucleus
Molecular Function: protein dimerization activity; DNA binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; heart morphogenesis; endothelial cell differentiation; Notch signaling pathway; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; multicellular organismal development; positive regulation of striated muscle cell differentiation; mesodermal cell migration; cardiac muscle cell differentiation; regulation of transcription, DNA-dependent; neurogenesis; negative regulation of mesodermal cell fate specification; negative regulation of endodermal cell fate specification; positive regulation of transcription from RNA polymerase II promoter; heart looping; negative regulation of transcription, DNA-dependent; positive regulation of Notch signaling pathway
Research Articles on Mesp1
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Product Notes
The Mesp1 mesp1 (Catalog #AAA9208168) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 62-91. The Mouse Mesp1 Antibody (Center) reacts with Mouse (Predicted Reactivity: Human) and may cross-react with other species as described in the data sheet. AAA Biotech's Mesp1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:500-1:2000. Researchers should empirically determine the suitability of the Mesp1 mesp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mesp1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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