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Knockout Validation (Knockout Validation: Lane 1: Wild-type HepG2 cell lysate;;Lane 2: MPP6 knockout HepG2 cell lysate;;Predicted MW: 63kDa ;Observed MW: 63kDa;Primary Ab: 5ug/ml Rabbit Anti-Mouse MPP6 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(#MBS2086047))

Rabbit anti-Mouse Membrane Protein, Palmitoylated 6 (MPP6) Polyclonal Antibody | anti-MPP6 antibody

FITC-Linked Polyclonal Antibody to Membrane Protein, Palmitoylated 6 (MPP6)

Gene Names
MPP6; VAM1; p55T; PALS2; VAM-1
Reactivity
Mouse
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Synonyms
Membrane Protein; Palmitoylated 6 (MPP6); Polyclonal Antibody; FITC-Linked Polyclonal Antibody to Membrane Protein; PALS2; VAM1; P55T; MAGUK P55 Subfamily Member 6; Veli-associated MAGUK 1; anti-MPP6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Concentration
500ug/ml (varies by lot)
Applicable Applications for anti-MPP6 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Immunogen
MPP6 (Val34~Cys235)
Conjugation
FITC
Cross Reactivity
Human, Mouse
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2032379

Knockout Validation

(Knockout Validation: Lane 1: Wild-type HepG2 cell lysate;;Lane 2: MPP6 knockout HepG2 cell lysate;;Predicted MW: 63kDa ;Observed MW: 63kDa;Primary Ab: 5ug/ml Rabbit Anti-Mouse MPP6 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(#MBS2086047))

Knockout Validation (Knockout Validation: Lane 1: Wild-type HepG2 cell lysate;;Lane 2: MPP6 knockout HepG2 cell lysate;;Predicted MW: 63kDa ;Observed MW: 63kDa;Primary Ab: 5ug/ml Rabbit Anti-Mouse MPP6 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(#MBS2086047))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
61,117 Da
NCBI Official Full Name
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6), isoform CRA_c
NCBI Official Synonym Full Names
membrane palmitoylated protein 6
NCBI Official Symbol
MPP6
NCBI Official Synonym Symbols
VAM1; p55T; PALS2; VAM-1
NCBI Protein Information
MAGUK p55 subfamily member 6
UniProt Protein Name
MAGUK p55 subfamily member 6
Protein Family
UniProt Gene Name
MPP6
UniProt Synonym Gene Names
VAM1; VAM-1

NCBI Description

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008]

Uniprot Description

VAM-1: a membrane-associated of the MAGUK family. Interacts with Lin7, which localizes to postsynaptic densities of neurons and epithelial cell-cell junctions.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7p15.3

Molecular Function: protein binding

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Product Notes

The MPP6 mpp6 (Catalog #AAA2046296) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FITC-Linked Polyclonal Antibody to Membrane Protein, Palmitoylated 6 (MPP6) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Membrane Protein, Palmitoylated 6 (MPP6) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the MPP6 mpp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Membrane Protein, Palmitoylated 6 (MPP6), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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