Western Blot (WB)
(Western blot analysis of 1) Hela, 2) 3T3, 3) PC12 with MEK5 Rabbit pAb EA222 diluted at 1:2,000.)
Rabbit MEK5 Polyclonal Antibody | anti-MEK5 antibody
MEK5 Rabbit pAb
Western Blot (WB)
(Western blot analysis of 1) Hela, 2) 3T3, 3) PC12 with MEK5 Rabbit pAb EA222 diluted at 1:2,000.)
Western Blot (WB)
(Western blot analysis of 1) Hela, 2) 3T3, 3) PC12 with MEK5 Rabbit pAb EA222 diluted at 1:2,000.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using MEK5(EA222)Rabbit pAb diluted at 1:500.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using MEK5(EA222)Rabbit pAb diluted at 1:500.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
Uniprot Description
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.
Research Articles on MEK5
Similar Products
Product Notes
The MEK5 map2k5 (Catalog #AAA8808338) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MEK5 Rabbit pAb reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "MEK5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
