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Western Blot (WB) (The anti-MEG2 Pab is used in Western blot to detect MEG2 in A549 cell lysate.)

Rabbit anti-Human MEG2 Polyclonal Antibody | anti-PTPN9 antibody

MEG2 Antibody (C-term)

Gene Names
PTPN9; MEG2; PTPMEG2
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MEG2; Polyclonal Antibody; MEG2 Antibody (C-term); Tyrosine-protein phosphatase non-receptor type 9; Protein-tyrosine phosphatase MEG2; PTPase MEG2; PTPN9; anti-PTPN9 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MEG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of human MEG2.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
477-505
Sequence Length
593
Applicable Applications for anti-PTPN9 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(The anti-MEG2 Pab is used in Western blot to detect MEG2 in A549 cell lysate.)

Western Blot (WB) (The anti-MEG2 Pab is used in Western blot to detect MEG2 in A549 cell lysate.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with MEG2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with MEG2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Related Product Information for anti-PTPN9 antibody
MEG2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
Product Categories/Family for anti-PTPN9 antibody
References
Kruger, J.M., et al., J. Biol. Chem. 277(4):2620-2628 (2002).
Qi, Y., et al., J. Cell. Biochem. 86(1):79-89 (2002).
Gu, M., et al., Proc. Natl. Acad. Sci. U.S.A. 89(7):2980-2984 (1992).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68020
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type 9
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 9
NCBI Official Symbol
PTPN9
NCBI Official Synonym Symbols
MEG2; PTPMEG2
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 9
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 9
UniProt Gene Name
PTPN9
UniProt Synonym Gene Names
PTPase MEG2
UniProt Entry Name
PTN9_HUMAN

NCBI Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq, Jul 2008]

Uniprot Description

PTPN9: Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus. Belongs to the protein-tyrosine phosphatase family. Non-receptor class 3 subfamily.

Protein type: Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.48

Chromosomal Location of Human Ortholog: 15q24.2

Cellular Component: cytoplasm

Molecular Function: protein binding; non-membrane spanning protein tyrosine phosphatase activity; protein tyrosine phosphatase activity

Biological Process: protein amino acid dephosphorylation

Research Articles on PTPN9

Similar Products

Product Notes

The PTPN9 ptpn9 (Catalog #AAA9205284) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 477-505. The MEG2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MEG2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the PTPN9 ptpn9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MEG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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