Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MECOM Polyclonal Antibody at dilution of 1:60(×200))
Rabbit anti-Human, Mouse MECOM Polyclonal Antibody | anti-MECOM antibody
MECOM Polyclonal Antibody
Gene Names
MECOM; EVI1; MDS1; KMT8E; PRDM3; RUSAT2; MDS1-EVI1; AML1-EVI-1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
MECOM; Polyclonal Antibody; MECOM Polyclonal Antibody; Ecotropic Virus Integration Site 1 Protein Homolog; MDS1 And EVI1 Complex Locus Protein; PR Domain 3; EVI1; MDS1; MDS1 And EVI1 Complex Locus Protein EVI1; MDS1 And EVI1 Complex Locus Protein MDS1; Ecotropic Viral Integration Site 1; Myelodysplasia Syndrome 1 Protein; Zinc Finger Protein Evi1; Oncogene EVI1; AML1-EVI-1; MDS1-EVI1; RUSAT2; KMT8E; PRDM3; anti-MECOM antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1.68mg/mL (varies by lot)
Sequence Length
1116
Applicable Applications for anti-MECOM antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:40-1:200
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Synthetic peptide of human MECOM
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MECOM Polyclonal Antibody at dilution of 1:60(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MECOM Polyclonal Antibody at dilution of 1:60(×200))
Related Product Information for anti-MECOM antibody
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Product Categories/Family for anti-MECOM antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
histone-lysine N-methyltransferase MECOM isoform a
NCBI Official Synonym Full Names
MDS1 and EVI1 complex locus
NCBI Official Symbol
MECOM
NCBI Official Synonym Symbols
EVI1; MDS1; KMT8E; PRDM3; RUSAT2; MDS1-EVI1; AML1-EVI-1
NCBI Protein Information
histone-lysine N-methyltransferase MECOM
UniProt Protein Name
MDS1 and EVI1 complex locus protein EVI1
Protein Family
UniProt Gene Name
MECOM
UniProt Synonym Gene Names
EVI1; EVI-1
UniProt Entry Name
EVI1_HUMAN
NCBI Description
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Research Articles on MECOM
Similar Products
Product Notes
The MECOM mecom (Catalog #AAA2561715) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MECOM Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MECOM can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:40-1:200 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the MECOM mecom for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MECOM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
