Western Blot (WB)
(Western Blot analysis of PC-3 cells using MCT4 Polyclonal Antibody)
Rabbit MCT4 Polyclonal Antibody | anti-MCT4 antibody
MCT4 Polyclonal Antibody
ELISA: 1:40000
Not yet tested in other applications.
Western Blot (WB)
(Western Blot analysis of PC-3 cells using MCT4 Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of PC-3 cells using MCT4 Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of lovo cells using MCT4 Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of lovo cells using MCT4 Polyclonal Antibody)
NCBI and Uniprot Product Information
NCBI Description
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]
Uniprot Description
SLC16A3: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 17q25
Cellular Component: nuclear membrane; membrane; integral to plasma membrane; plasma membrane; actin cytoskeleton
Molecular Function: monocarboxylic acid transmembrane transporter activity; symporter activity; lactate transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity
Biological Process: cellular metabolic process; monocarboxylic acid transport; blood coagulation; pyruvate metabolic process; leukocyte migration; transmembrane transport
Research Articles on MCT4
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Product Notes
The MCT4 slc16a3 (Catalog #AAA9405369) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MCT4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MCT4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Western Blot: 1:500 - 1:2000 ELISA: 1:40000 Not yet tested in other applications. Researchers should empirically determine the suitability of the MCT4 slc16a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCT4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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