Goat anti-Murine MCP3 MCP3 Polyclonal Antibody | anti-MCP3 antibody

MCP3 antibody

Cat. Num. AAA535851

• Reactivity: Murine MCP3
• Applications: ELISA, Western Blot
• Synonyms: MCP3; Polyclonal Antibody; MCP3 antibody; Polyclonal MCP3; Anti-MCP3; MARC; Monocyte Chemotactic-3; MCP 3; MCP-3; CCL7; anti-MCP3 antibody

• Host: Goat
• Reactivity: Murine MCP3
• Clonality: Polyclonal
• Specificity: Murine MCP3
• Form/Format: Lyophilized from PBS, pH 7.2.
• Sequence Length: 109

• Applicable Applications for anti-MCP3 antibody: ELISA (EIA), Inhibition, Western Blot (WB)
• Application Notes: ELISA: 0.5-2 ug/ml; Inhibition: 4-6 ug/ml; WB: 0.1-0.2 ug/ml
• Biological Significance: MCP3 is a chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. It augments monocyte anti-tumor activity and induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
• Immunogen: MCP3 antibody was raised in goat using highly pure recombinant murine MCP-3 as the immunogen.
• Preparation and Storage: Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.

Related Product Information for anti-MCP3 antibody

Affinity purified Goat polyclonal MCP3 antibody

Product Categories/Family for anti-MCP3 antibody

Cytokines & Growth Factors; Purified Polyclonal Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 313708
• UniProt Accession #: P80098; Q569J6
• Molecular Weight: 9.0 kDa (predicted detection band MW)
• NCBI Official Full Name: monocyte chemotactic protein-3
• UniProt Protein Name: C-C motif chemokine 7
• Protein Family: Meiotic coiled-coil protein
• UniProt Gene Name: CCL7
• UniProt Synonym Gene Names: MCP3; SCYA6; SCYA7; MCP-3
• UniProt Entry Name: CCL7_HUMAN

Uniprot Description

CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space; extracellular region

Molecular Function: heparin binding; CCR1 chemokine receptor binding; CCR2 chemokine receptor binding; chemokine activity

Biological Process: cellular calcium ion homeostasis; regulation of cell shape; monocyte chemotaxis; cell-cell signaling; eosinophil chemotaxis; response to gamma radiation; cytoskeleton organization and biogenesis; immune response; chemotaxis; inflammatory response; signal transduction; positive regulation of cell migration