Rabbit MBL2/Mannose Binding Protein Polyclonal Antibody | anti-MBL2 antibody

Anti-MBL2/Mannose Binding Protein Antibody

Cat. Num. AAA2401946

• Gene Names: MBL2; MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC
• Reactivity: Human; Predicted: Mouse, Rat
• Applications: Immunohistochemistry, Immunohistochemistry, Western Blot
• Purity: Affinity Purified
• Synonyms: MBL2/Mannose Binding Protein; Polyclonal Antibody; Anti-MBL2/Mannose Binding Protein Antibody; Mouse Monoclonal (IgG1) to Human MBL2/Mannose Binding Protein; MBL2; Mannan-binding lectin; Mannan-binding protein; MBL2D; MBPD; MBL; Mannose-binding lectin; MBP-C; MBP1; COLEC1; Collectin-1; HSMBPC; Mannose-binding protein C; anti-MBL2 antibody

• Host: Rabbit
• Reactivity: Human; Predicted: Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human MBL2/Mannose Binding Protein
• Purity/Purification: Affinity Purified
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
• Sequence Length: 248

• Applicable Applications for anti-MBL2 antibody: Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IHC: 1:50-1:200; IHC-P: 1:100; WB: 1:500-1:2000
• Immunogen: Recombinant protein of human MBL2.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C.; Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of extracts of various cell lines.)

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using MBL2 antibody.)

Related Product Information for anti-MBL2 antibody

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to earlyapoptotic cells, facilitating their uptake by macrophages. May bind DNA.

NCBI and Uniprot Product Information

• NCBI GI #: 4557739
• NCBI GeneID: 4153
• NCBI Accession #: NP_000233.1
• NCBI GenBank Nucleotide #: NM_000242.2
• UniProt Accession #: P11226; Q4VB12; Q4VB13; Q4VB14; Q5SQS3; Q86SI4; Q96KE4; Q96TF7; Q96TF8; Q96TF9
• Molecular Weight: 26,144 Da
• NCBI Official Full Name: mannose-binding protein C
• NCBI Official Synonym Full Names: mannose binding lectin 2
• NCBI Official Symbol: MBL2
• NCBI Official Synonym Symbols: MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC
• NCBI Protein Information: mannose-binding protein C
• UniProt Protein Name: Mannose-binding protein C
• Protein Family: Mannose-binding protein
• UniProt Gene Name: MBL2
• UniProt Synonym Gene Names: COLEC1; MBL; MBP-C

NCBI Description

This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]

Uniprot Description

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.