Western Blot (WB)
(Western blot analysis of MATN1 in mouse liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 ug/mL.)
Rabbit MATN1 Polyclonal Antibody | anti-MATN1 antibody
MATN1 Antibody
Gene Names
MATN1; CMP; CRTM
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
MATN1; Polyclonal Antibody; MATN1 Antibody; Matrilin 1; Cartilage matrix protein; CMP; CRTM; anti-MATN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
496
Applicable Applications for anti-MATN1 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 12 amino acid peptide from near the amino terminus of human MATN1.
Target Name
MATN1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of MATN1 in mouse liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of MATN1 in mouse liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-MATN1 antibody
Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.
Product Categories/Family for anti-MATN1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,701 Da
NCBI Official Full Name
cartilage matrix protein
NCBI Official Synonym Full Names
matrilin 1, cartilage matrix protein
NCBI Official Symbol
MATN1
NCBI Official Synonym Symbols
CMP; CRTM
NCBI Protein Information
cartilage matrix protein
UniProt Protein Name
Cartilage matrix protein
Protein Family
UniProt Gene Name
MATN1
UniProt Synonym Gene Names
CMP; CRTM
UniProt Entry Name
MATN1_HUMAN
NCBI Description
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. Mutations of this gene have been associated with variety of inherited chondrodysplasias. [provided by RefSeq, Jul 2008]
Uniprot Description
MATN1: Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 1p35
Cellular Component: proteinaceous extracellular matrix; extracellular region
Molecular Function: protein binding; extracellular matrix structural constituent
Biological Process: extracellular matrix organization and biogenesis; protein complex assembly; regulation of bone mineralization
Research Articles on MATN1
Similar Products
Product Notes
The MATN1 matn1 (Catalog #AAA9403026) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MATN1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MATN1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the MATN1 matn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MATN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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