Rabbit MARF1 Polyclonal Antibody | anti-MARF1 antibody
MARF1 Antibody
Gene Names
KIAA0430; LKAP; MARF1; PPP1R34
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
MARF1; Polyclonal Antibody; MARF1 Antibody; KIAA0430; Limkain-b1; LKAP; LKAP_HUMAN; Meiosis arrest female 1; Meiosis arrest female protein 1; PPP1R34; Protein phosphatase 1; regulatory subunit 34; anti-MARF1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
MARF1 Antibody detects endogenous levels of MARF1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-MARF1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human MARF1.
Conjugation
Unconjugated
Subunit Structure
Interacts with LIMK2.
Function
Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-MARF1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,458 Da
NCBI Official Full Name
meiosis arrest female protein 1 isoform 2
NCBI Official Synonym Full Names
KIAA0430
NCBI Official Symbol
KIAA0430
NCBI Official Synonym Symbols
LKAP; MARF1; PPP1R34
NCBI Protein Information
meiosis arrest female protein 1
UniProt Protein Name
Meiosis arrest female protein 1
Protein Family
UniProt Gene Name
KIAA0430
UniProt Synonym Gene Names
LKAP; MARF1
UniProt Entry Name
MARF1_HUMAN
NCBI Description
This gene encodes a putative peroxisomal protein that appears to be conserved across Euteleostomi. In humans, it may be autoantigenic. [provided by RefSeq, Jul 2010]
Uniprot Description
LKAP: Essential regulator of oogenesis required for female meiotic progression. Acts by down-regulating RNA transcripts, either at transcriptional of post-transcriptional level. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 16p13.11
Cellular Component: membrane; peroxisome
Molecular Function: RNA binding; nucleotide binding
Biological Process: oogenesis; regulation of gene expression; double-strand break repair; female meiosis
Research Articles on MARF1
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Product Notes
The MARF1 kiaa0430 (Catalog #AAA9630661) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MARF1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MARF1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the MARF1 kiaa0430 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MARF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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