Human Magnesium transporter NIPA1 (NIPA1) ELISA Kit | NIPA1 elisa kit

Human Magnesium transporter NIPA1 (NIPA1) ELISA Kit

Cat. Num. AAA167348

• Gene Names: NIPA1; FSP3; SPG6; SLC57A1
• Reactivity: Human
• Synonyms: Magnesium transporter NIPA1 (NIPA1); Human Magnesium transporter NIPA1 (NIPA1) ELISA Kit; NIPA1 elisa kit

• Reactivity: Human
• Sequence Length: 254

• Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.05ng/ml - 30ng/ml
• Sensitivity: 0.027ng/ml
• Intra-Assay: CV<8%
• Inter-Assay: CV<10%
• Preparation and Storage: Store at 2 to 8 degree C for 6 months.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for NIPA1 elisa kit

Intended Uses: This sandwich kit is for the accurate quantitative detection of human Magnesium Transporter NIPA1 (also known as NIPA1) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human NIPA1 antibody. NIPA1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human NIPA1 Antibody is added and binds to NIPA1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated NIPA1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human NIPA1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

NCBI and Uniprot Product Information

• NCBI GI #: 214010179
• NCBI GeneID: 123606
• NCBI Accession #: NP_001135747.1
• NCBI GenBank Nucleotide #: NM_001142275.1
• UniProt Accession #: Q7RTP0; Q5HYA9; Q7KZB0; Q86XW4; B2RA76
• Molecular Weight: 27,310 Da
• NCBI Official Full Name: magnesium transporter NIPA1 isoform 2
• NCBI Official Synonym Full Names: NIPA magnesium transporter 1
• NCBI Official Symbol: NIPA1
• NCBI Official Synonym Symbols: FSP3; SPG6; SLC57A1
• NCBI Protein Information: magnesium transporter NIPA1
• UniProt Protein Name: Magnesium transporter NIPA1
• Protein Family: Magnesium transporter
• UniProt Gene Name: NIPA1
• UniProt Synonym Gene Names: SPG6

NCBI Description

This gene encodes a magnesium transporter that associates with early endosomes and the cell surface in a variety of neuronal and epithelial cells. This protein may play a role in nervous system development and maintenance. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with autosomal dominant spastic paraplegia 6. [provided by RefSeq, Nov 2008]

Uniprot Description

Acts as a Mg2+ transporter. Can also transport other divalent cations such as Fe2+, Sr2+, Ba2+, Mn2+ and Co2+ but to a much less extent than Mg2+ ().