Rabbit MAPKAPK 2 Polyclonal Antibody | anti-MAPKAPK 2 antibody
MAPKAPK 2 antibody
NCBI and Uniprot Product Information
Uniprot Description
MAPKAPK2: a member of the MAPKAPK family of protein kinases. It is phosphorylated and activated by p38 in response to cytokines, stress and chemotactic factors.MAPKAPK-2 is apparently a direct target of p38 MAPK. HSP27 is one of its in vivo substrates. Two transcript variants encoding two different isoforms have been described.
Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; Kinase, protein; CAMK group; MAPKAPK family; MAPKAPK subfamily
Cellular Component: nucleoplasm; centrosome; cytoplasm; nucleus
Molecular Function: transferase activity; calmodulin binding; protein serine/threonine kinase activity; signal transducer activity; protein binding; calcium-dependent protein serine/threonine kinase activity; calmodulin-dependent protein kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; mitogen-activated protein kinase binding; kinase activity; ATP binding; protein kinase activity
Biological Process: positive regulation of tumor necrosis factor biosynthetic process; mRNA stabilization; protein amino acid autophosphorylation; cellular response to stress; MAPKKK cascade; response to lipopolysaccharide; protein amino acid phosphorylation; peptidyl-serine phosphorylation; response to cytokine stimulus; toll-like receptor signaling pathway; regulation of interleukin-6 production; response to stress; regulation of tumor necrosis factor production; G2/M transition DNA damage checkpoint; inflammatory response; vascular endothelial growth factor receptor signaling pathway; response to DNA damage stimulus; inner ear development; phosphorylation
Research Articles on MAPKAPK 2
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Product Notes
The MAPKAPK 2 mapkapk2 (Catalog #AAA837314) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MAPKAPK 2 can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the MAPKAPK 2 mapkapk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAPKAPK 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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