Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using MAP4K5 antibody.)
Rabbit MAP4K5 Polyclonal Antibody | anti-MAP4K5 antibody
MAP4K5 Polyclonal Antibody
Gene Names
MAP4K5; KHS; GCKR; KHS1; MAPKKKK5
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
MAP4K5; Polyclonal Antibody; MAP4K5 Polyclonal Antibody; GCKR; KHS; KHS1; MAPKKKK5; anti-MAP4K5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MAP4K5 polyclonal antibody detects endogenous levels of MAP4K5 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
846
Applicable Applications for anti-MAP4K5 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IF: 1:50-1:100
IF: 1:50-1:100
Immunogen
Recombinant protein of human MAP4K5
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using MAP4K5 antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cells using MAP4K5 antibody.)
Related Product Information for anti-MAP4K5 antibody
This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
mitogen-activated protein kinase kinase kinase kinase 5
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase kinase kinase 5
NCBI Official Symbol
MAP4K5
NCBI Official Synonym Symbols
KHS; GCKR; KHS1; MAPKKKK5
NCBI Protein Information
mitogen-activated protein kinase kinase kinase kinase 5
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase kinase 5
Protein Family
UniProt Gene Name
MAP4K5
UniProt Synonym Gene Names
KHS; MEK kinase kinase 5; MEKKK 5
NCBI Description
This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Research Articles on MAP4K5
Similar Products
Product Notes
The MAP4K5 map4k5 (Catalog #AAA3010663) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAP4K5 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAP4K5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:2000 IF: 1:50-1:100. Researchers should empirically determine the suitability of the MAP4K5 map4k5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAP4K5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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