Western Blot (WB)
(Mouse Map3k3 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Map3k3 antibody detected the Map3k3 protein (arrow).)
Rabbit anti-Mouse Map3k3 Polyclonal Antibody | anti-Map3k3 antibody
Mouse Map3k3 Antibody (Center)
Gene Names
Map3k3; Mekk3; MAPKKK3; AW548911; mKIAA4031
Reactivity
Mouse
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Map3k3; Polyclonal Antibody; Mouse Map3k3 Antibody (Center); Mitogen-activated protein kinase kinase kinase 3; MAPK/ERK kinase kinase 3; MEK kinase 3; MEKK 3; Mekk3; anti-Map3k3 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Map3k3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of mouse Map3k3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.47 (varies by lot)
Sequence Positions
228-257
Sequence Length
626
Applicable Applications for anti-Map3k3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
MOUSE
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Mouse Map3k3 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Map3k3 antibody detected the Map3k3 protein (arrow).)
Western Blot (WB)
(Mouse Map3k3 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Map3k3 antibody detected the Map3k3 protein (arrow).)
Related Product Information for anti-Map3k3 antibody
Component of a protein kinase signal transduction cascade. Map3k3 mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.
Product Categories/Family for anti-Map3k3 antibody
References
Zhang, J., et al. J. Immunol. 185(6):3554-3563(2010)
Yu, L., et al. Cancer Res. 70(4):1334-1343(2010)
Sun, W., et al. Cell. Signal. 21(10):1488-1494(2009)
Retting, K.N., et al. Development 136(7):1093-1104(2009)
Wang, X., et al. J. Immunol. 182(6):3597-3608(2009)
Yu, L., et al. Cancer Res. 70(4):1334-1343(2010)
Sun, W., et al. Cell. Signal. 21(10):1488-1494(2009)
Retting, K.N., et al. Development 136(7):1093-1104(2009)
Wang, X., et al. J. Immunol. 182(6):3597-3608(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70776
NCBI Official Full Name
mitogen-activated protein kinase kinase kinase 3
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase kinase 3
NCBI Official Symbol
Map3k3
NCBI Official Synonym Symbols
Mekk3; MAPKKK3; AW548911; mKIAA4031
NCBI Protein Information
mitogen-activated protein kinase kinase kinase 3
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase 3
UniProt Gene Name
Map3k3
UniProt Synonym Gene Names
Mekk3; MEK kinase 3; MEKK 3
UniProt Entry Name
M3K3_MOUSE
Uniprot Description
MEKK3: a protein kinase of the STE11 family. Phosphorylated and activated by MLK3 and TAK1. Phosphorylates and activates MEK5.
Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, STE; EC 2.7.11.25; STE group; STE11 family
Cellular Component: intracellular
Molecular Function: MAP kinase kinase activity; transferase activity; protein serine/threonine kinase activity; protein binding; MAP kinase kinase kinase activity; metal ion binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: blood vessel development; activation of MAPK activity; protein amino acid autophosphorylation; phosphorylation; protein amino acid phosphorylation
Research Articles on Map3k3
Similar Products
Product Notes
The Map3k3 map3k3 (Catalog #AAA9213970) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 228-257. The Mouse Map3k3 Antibody (Center) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Map3k3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Map3k3 map3k3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Map3k3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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