Rabbit MAP2 Polyclonal Antibody | anti-MAP2 antibody

MAP2 Rabbit Polyclonal

Cat. Num. AAA7601209

• Gene Names: MAP2; MAP2A; MAP2B; MAP2C
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunofluorescence, Immunoprecipitation, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: MAP2; Polyclonal Antibody; MAP2 Rabbit Polyclonal; anti-MAP2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 1064

• Applicable Applications for anti-MAP2 antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC)
• Immunogen: Microtubule-associated protein 2
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain using MBS7601209 (MAP2 antibody) at dilution of 1:100)

Western Blot (WB)

(SH-SY5Y cells were subjected to SDS PAGE followed by western blot with MBS7601209 (MAP2 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 44890629
• NCBI GeneID: 4133
• Molecular Weight: 58,954 Da
• NCBI Official Full Name: MAP2 protein, partial
• NCBI Official Synonym Full Names: microtubule associated protein 2
• NCBI Official Symbol: MAP2
• NCBI Official Synonym Symbols: MAP2A; MAP2B; MAP2C
• NCBI Protein Information: microtubule-associated protein 2
• UniProt Protein Name: Microtubule-associated protein 2
• Protein Family: Microtubule-associated protein
• UniProt Gene Name: MAP2
• UniProt Synonym Gene Names: MAP-2
• UniProt Entry Name: MTAP2_HUMAN

NCBI Description

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]

Uniprot Description

MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 2q34-q35

Cellular Component: cytoplasm; microtubule; microtubule associated complex; neuron projection; nucleolus

Molecular Function: calmodulin binding; microtubule binding; protein binding; structural molecule activity

Biological Process: central nervous system neuron development; dendrite morphogenesis; microtubule bundle formation; microtubule cytoskeleton organization and biogenesis; neurite development