Rabbit MAP1B Polyclonal Antibody | anti-MAP1B antibody

MAP1B (Microtubule Associated Protein 1B, MAP5, FUTSCH) (HRP)

Cat. Num. AAA6425290

• Gene Names: MAP1B; MAP5; FUTSCH; PPP1R102
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Purified by affinity chromatography.
• Synonyms: MAP1B; Polyclonal Antibody; MAP1B (Microtubule Associated Protein 1B; MAP5; FUTSCH) (HRP); anti-MAP1B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes MAP1B. Species Crossreactivity: human, mouse, rat
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-MAP1B antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000; Applications are based on unconjugated antibody.
• Immunogen: Recombinant protein corresponding to human MAP1B.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of extracts of Mouse cerebellum, using MAP1B antibody.)

Product Categories/Family for anti-MAP1B antibody

Antibodies; Microtubule-associated Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 317373388
• NCBI GeneID: 4131
• UniProt Accession #: P46821; A2BDK5
• Molecular Weight: 2468
• NCBI Official Full Name: Microtubule-associated protein 1B
• NCBI Official Synonym Full Names: microtubule-associated protein 1B
• NCBI Official Symbol: MAP1B
• NCBI Official Synonym Symbols: MAP5; FUTSCH; PPP1R102
• NCBI Protein Information: microtubule-associated protein 1B; MAP-1B; protein phosphatase 1, regulatory subunit 102
• UniProt Protein Name: Microtubule-associated protein 1B
• Protein Family: Methionine aminopeptidase
• UniProt Gene Name: MAP1B
• UniProt Synonym Gene Names: MAP-1B
• UniProt Entry Name: MAP1B_HUMAN

NCBI Description

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

MAP1B: the function of brain MAPS is essentially unknown. Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q13

Cellular Component: microtubule; microtubule associated complex; postsynaptic density; cytoplasm; dendritic spine; plasma membrane; cell junction; cytosol

Molecular Function: protein binding; microtubule binding; structural molecule activity

Biological Process: negative regulation of intracellular transport; axon extension; positive regulation of axon extension; dendrite development; cellular process; microtubule bundle formation; mitochondrion transport along microtubule