Rabbit anti-Human, Mouse MAGEA9 Polyclonal Antibody | anti-MAGEA9 antibody

MAGEA9 (Melanoma-associated Antigen 9, MAGE-9 Antigen, Cancer/Testis Antigen 1.9, CT1.9, MAGE9, MAGEA9A, MGC8421) (HRP)

Cat. Num. AAA6384624

• Gene Names: MAGEA9; CT1.9; MAGE9
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MAGEA9; Polyclonal Antibody; MAGEA9 (Melanoma-associated Antigen 9; MAGE-9 Antigen; Cancer/Testis Antigen 1.9; CT1.9; MAGE9; MAGEA9A; MGC8421) (HRP); anti-MAGEA9 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human MAGEA9. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-MAGEA9 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human MAGEA9, aa1-315 (NP_005356.1).
• Immunogen Sequence: MSLEQRSPHCKPDEDLEAQGEDLGLMGAQEPTGEEEETTSSSDSKEEEVSAAGSSSPPQSPQGGASSSISVYYTLWSQFDEGSSSQEEEEPSSSVDPAQLEFMFQEALKLKVAELVHFLLHKYRVKEPVTKAEMLESVIKNYKRYFPVIFGKASEFMQVIFGTDVKEVDPAGHSYILVTALGLSCDSMLGDGHSMPKAALLIIVLGVILTKDNCAPEEVIWEALSVMGVYVGKEHMFYGEPRKLLTQDWVQENYLEYRQVPGSDPAHYEFLWGSKAHAETSYEKVINYLVMLNAREPICYPSLYEEVLGEEQEGV
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(MAGEA9 rabbit polyclonal antibody. Western Blot analysis of MAGEA9 expression in human spleen.)

Western Blot (WB)

(MAGEA9 rabbit polyclonal antibody. Western Blot analysis of MAGEA9 expression in HeLa.)

Western Blot (WB)

(Western Blot analysis of MAGEA9 expression in transfected 293T cell line by MAGEA9 polyclonal antibody. Lane 1: MAGEA9 transfected lysate (35.1kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-MAGEA9 antibody

MAGEA9 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.

Product Categories/Family for anti-MAGEA9 antibody

Antibodies; Cancer Markers

NCBI and Uniprot Product Information

• NCBI GI #: 4885473
• NCBI GeneID: 4108
• NCBI Accession #: NP_005356.1
• NCBI GenBank Nucleotide #: NM_005365.4
• UniProt Accession #: P43362; Q7Z5K4; Q92910; A8K8A7
• Molecular Weight: 35,088 Da
• NCBI Official Full Name: melanoma-associated antigen 9
• NCBI Official Synonym Full Names: melanoma antigen family A, 9
• NCBI Official Symbol: MAGEA9
• NCBI Official Synonym Symbols: CT1.9; MAGE9
• NCBI Protein Information: melanoma-associated antigen 9; MAGE-9 antigen; cancer/testis antigen 1.9; cancer/testis antigen family 1, member 9
• UniProt Protein Name: Melanoma-associated antigen 9
• Protein Family: Melanoma-associated antigen
• UniProt Gene Name: MAGEA9
• UniProt Synonym Gene Names: MAGE9; MAGEA9A; CT1.9
• UniProt Entry Name: MAGA9_HUMAN

NCBI Description

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]

Uniprot Description

MAGE-A9: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.

Protein type: Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: Xq28