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Western Blot (WB) (Western Blot analysis of A549, 231, PC3 and hela cell using MAD2L1BP Polyclonal Antibody at dilution of 1:675)

Rabbit MAD2L1BP Polyclonal Antibody | anti-MAD2L1BP antibody

MAD2L1BP Polyclonal Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
MAD2L1BP; Polyclonal Antibody; MAD2L1BP Polyclonal Antibody; CMT2; RP1-261G23.6; anti-MAD2L1BP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.7mg/mL (varies by lot)
Sequence Length
274
Applicable Applications for anti-MAD2L1BP antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
Recombinant protein of human MAD2L1BP
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of A549, 231, PC3 and hela cell using MAD2L1BP Polyclonal Antibody at dilution of 1:675)

Western Blot (WB) (Western Blot analysis of A549, 231, PC3 and hela cell using MAD2L1BP Polyclonal Antibody at dilution of 1:675)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human cervical cancer using MAD2L1BP Polyclonal Antibody at dilution of 1:65)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human cervical cancer using MAD2L1BP Polyclonal Antibody at dilution of 1:65)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human prostate cancer using MAD2L1BP Polyclonal Antibody at dilution of 1:65)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human prostate cancer using MAD2L1BP Polyclonal Antibody at dilution of 1:65)
Related Product Information for anti-MAD2L1BP antibody
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Product Categories/Family for anti-MAD2L1BP antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
34,676 Da
NCBI Official Full Name
MAD2L1BP
UniProt Protein Name
MAD2L1-binding protein
Protein Family
UniProt Gene Name
MAD2L1BP
UniProt Synonym Gene Names
CMT2; KIAA0110
UniProt Entry Name
MD2BP_HUMAN

Uniprot Description

MAD2L1BP: May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. Belongs to the MAD2L1BP family.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: intracellular membrane-bound organelle; cytoplasm; nucleolus; spindle; nucleus

Molecular Function: protein binding

Biological Process: mitotic cell cycle checkpoint; regulation of exit from mitosis

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Product Notes

The MAD2L1BP mad2l1bp (Catalog #AAA2520558) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAD2L1BP Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAD2L1BP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the MAD2L1BP mad2l1bp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAD2L1BP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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