Sheep anti-Human Macrophage Inflammatory Protein-1a Polyclonal Antibody | anti-CCL4L1 antibody

Macrophage Inflammatory Protein-1a (MIP-1a)

Cat. Num. AAA621030

• Gene Names: CCL4L1; LAG1; CCL4L; LAG-1; SCYA4L; AT744.2
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Gel Super Shift Assay
• Purity: Purified; Purified
• Synonyms: Macrophage Inflammatory Protein-1a; Polyclonal Antibody; Macrophage Inflammatory Protein-1a (MIP-1a); Anti -Macrophage Inflammatory Protein-1a (MIP-1a); anti-CCL4L1 antibody

• Host: Sheep
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human MIP-1a.
• Purity/Purification: Purified; Purified
• Form/Format: Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-CCL4L1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Gel Shift Assay (GS/EMSA)
• Application Notes: Suitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry, Immunoassays, development of rapid tests and other antibody recognition assays.
• Immunogen: Recombinant corresponding to aa27-92 from human MIP-1, fused to 6x His-tag at N-terminal, expressed in E. coli.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-CCL4L1 antibody

MIP-1 alpha is a member of the CC chemokine family of proteins which have been shown to be produced by numerous cell types including activated T cells, B cells, monocytes, mast cells and endothelial cells. MIP-1a acts as a monocyte chemoattractant and has been shown to act as a stem cell inhibitory factor.

Product Categories/Family for anti-CCL4L1 antibody

Antibodies; Abs to Growth Factors; Cytokines

NCBI and Uniprot Product Information

• NCBI GI #: 20384896
• NCBI GeneID: 9560
• UniProt Accession #: Q8NHW4; Q50EM1; Q50EM2; Q50EM3; Q50EM4; Q50EM5; Q50EM6; Q50EM7; Q50EM8; Q569J2; B2RUZ3; B7ZMA8
• Molecular Weight: 10,166 Da
• NCBI Official Full Name: macrophage inflammatory protein-1b2
• NCBI Official Synonym Full Names: chemokine (C-C motif) ligand 4-like 1
• NCBI Official Symbol: CCL4L1
• NCBI Official Synonym Symbols: LAG1; CCL4L; LAG-1; SCYA4L; AT744.2
• NCBI Protein Information: C-C motif chemokine 4-like; MIP-1-beta; macrophage inflammatory protein-1b2; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; monocyte adherence-induced protein 5-alpha
• UniProt Protein Name: C-C motif chemokine 4-like
• Protein Family: C-C motif chemokine
• UniProt Gene Name: CCL4L1
• UniProt Synonym Gene Names: CCL4L; LAG1; SCYA4L1; LAG-1; MIP-1-beta
• UniProt Entry Name: CC4L_HUMAN

NCBI Description

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is similar to CCL4 which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals; most individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The human genome reference assembly contains two copies of this gene. This record represents the more centromeric gene. [provided by RefSeq, Jul 2008]

Uniprot Description

CCL4L1: Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral blood monocytes that express CCR5. Belongs to the intercrine beta (chemokine CC) family. 10 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted; Chemokine

Chromosomal Location of Human Ortholog: 17q12