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Rabbit anti-Human M3K14 Polyclonal Antibody | anti-M3K14 antibody

M3K14 Polyclonal Antibody

Gene Names
MAP3K14; HS; NIK; HSNIK; FTDCR1B
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
M3K14; Polyclonal Antibody; M3K14 Polyclonal Antibody; Mitogen-activated protein kinase kinase kinase 14; EC 2.7.11.25; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIK; MAP3K14; NIK; anti-M3K14 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Sequence Length
947
Applicable Applications for anti-M3K14 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-2000
ELISA: 1:5000-20000
Immunogen
Synthesized peptide derived from human protein. at AA range: 90-170
Preparation and Storage
Store at-20 degree C for 1 year.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
104
NCBI Official Full Name
mitogen-activated protein kinase kinase kinase 14
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase kinase 14
NCBI Official Symbol
MAP3K14
NCBI Official Synonym Symbols
HS; NIK; HSNIK; FTDCR1B
NCBI Protein Information
mitogen-activated protein kinase kinase kinase 14
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase 14
UniProt Gene Name
MAP3K14
UniProt Synonym Gene Names
NIK; HsNIK

NCBI Description

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]

Uniprot Description

Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.

Research Articles on M3K14

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Product Notes

The M3K14 map3k14 (Catalog #AAA8530948) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The M3K14 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's M3K14 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-2000 ELISA: 1:5000-20000. Researchers should empirically determine the suitability of the M3K14 map3k14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "M3K14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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