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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver tissue using MBS1495618 at dilution of 1:100)

Rabbit anti-Human LYRM1 Polyclonal Antibody | anti-LYRM1 antibody

LYRM1 Antibody

Gene Names
LYRM1; A211C6.1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%, Protein G Purified
Synonyms
LYRM1; Polyclonal Antibody; LYRM1 Antibody; LYR motif-containing protein 1; anti-LYRM1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
122
Applicable Applications for anti-LYRM1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC:1:20-1:200
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human LYR motif-containing protein 1 protein
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver tissue using MBS1495618 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver tissue using MBS1495618 at dilution of 1:100)
Related Product Information for anti-LYRM1 antibody
May promote cell proliferation and inhibition of apoptosis of preadipocytes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,282 Da
NCBI Official Full Name
LYR motif-containing protein 1
NCBI Official Synonym Full Names
LYR motif containing 1
NCBI Official Symbol
LYRM1
NCBI Official Synonym Symbols
A211C6.1
NCBI Protein Information
LYR motif-containing protein 1
UniProt Protein Name
LYR motif-containing protein 1
UniProt Gene Name
LYRM1
UniProt Entry Name
LYRM1_HUMAN

NCBI Description

The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Uniprot Description

LYRM1: May promote cell proliferation and inhibition of apoptosis of preadipocytes. When overexpressed, may be involved in obesity- associated insulin resistance, possibly by causing mitochondrial dysfunction in adipocytes. Belongs to the complex I LYR family.

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: intercellular bridge; mitochondrion; nucleoplasm

Research Articles on LYRM1

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Product Notes

The LYRM1 lyrm1 (Catalog #AAA1495618) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LYRM1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LYRM1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC:1:20-1:200. Researchers should empirically determine the suitability of the LYRM1 lyrm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LYRM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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