NCBI and Uniprot Product Information
Uniprot Description
AMICA1: an adhesion molecule that may function in the migration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells. Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells. Three alternatively spliced isoforms have been described.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: plasma membrane; tight junction
Molecular Function: cell adhesion molecule binding; integrin binding; protein homodimerization activity
Biological Process: gamma-delta T cell activation; heterophilic cell adhesion; leukocyte migration; neutrophil chemotaxis; positive regulation of epithelial cell proliferation involved in wound healing; regulation of immune response
Research Articles on JAML1
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Product Notes
The JAML1 jaml (Catalog #AAA9418225) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JAML1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's JAML1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500-1:2000. Researchers should empirically determine the suitability of the JAML1 jaml for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JAML1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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