Rabbit anti-Mouse Lymphotactin Polyclonal Antibody | anti-Xcl1 antibody

Lymphotactin Antibody

Cat. Num. AAA841421

• Gene Names: Xcl1; LTN; ATAC; Lptn; SCM-1; Scyc1; SCM-1a; AI661682
• Reactivity: Mouse
• Applications: Western Blot, Immunoprecipitation
• Purity: Affinity purified
• Synonyms: Lymphotactin; Polyclonal Antibody; Lymphotactin Antibody; C motif chemokine 1; Cytokine SCM-1; Small-inducible cytokine C1; anti-Xcl1 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purified
• Form/Format: 100 ug (0.5 mg/ml) Protein A purified rabbit anti-mouse Lymphotactin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.; Appearance: Colorless liquid
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 114

• Applicable Applications for anti-Xcl1 antibody: Western Blot (WB), Immunoprecipitation (IP)
• Application Notes: Western blot analysis (0.5-4 ug/ml) and immunoprecipitation (4-8 ug/ml). However, the optimal conditions should be determined individually.
• Immunogen: E. coli-expressed mouse lymphotactin (a.a. 1-92)
• Handling: The antibody solution should be gently mixed before use.
• Preparation and Storage: At -20 degree C; Shelf Life: 12 months

Testing Data

Related Product Information for anti-Xcl1 antibody

Background: Lymphotactin is the only C chemokine so far identified which has a single cysteine residue near the amino terminus. It has 114 amino acids with a 22 amino acids signal peptide. It is produced in activated CD8+ T cells and NK cells. Lymphotactin attracts both T lymphocytes and NK cells.

NCBI and Uniprot Product Information

• NCBI GI #: 6678712
• NCBI GeneID: 16963
• NCBI Accession #: NP_032536
• NCBI GenBank Nucleotide #: NM_008510.1
• Molecular Weight: 12,467 Da
• NCBI Official Full Name: lymphotactin
• NCBI Official Synonym Full Names: chemokine (C motif) ligand 1
• NCBI Official Symbol: Xcl1
• NCBI Official Synonym Symbols: LTN; ATAC; Lptn; SCM-1; Scyc1; SCM-1a; AI661682
• NCBI Protein Information: lymphotactin
• UniProt Protein Name: Lymphotactin
• Protein Family: Lymphotactin
• UniProt Gene Name: Xcl1
• UniProt Synonym Gene Names: Lptn; Ltn; Scyc1
• UniProt Entry Name: XCL1_MOUSE

Uniprot Description

XCL1: Chemotactic activity for lymphocytes but not for monocytes or neutrophils. Belongs to the intercrine gamma family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Cellular Component: extracellular space; cell; extracellular region; intracellular; cytosol

Molecular Function: protein homodimerization activity; chemokine activity; chemokine receptor binding; cytokine activity

Biological Process: positive regulation of T cell mediated cytotoxicity; response to virus; negative regulation of transcription factor activity; positive regulation of T cell cytokine production; positive regulation of leukocyte chemotaxis; positive regulation of immune response to tumor cell; negative regulation of T cell cytokine production; chemotaxis; positive regulation of interleukin-10 production; negative regulation of interleukin-2 production; cell-cell signaling; release of sequestered calcium ion into cytosol; negative regulation of interferon-gamma production; positive regulation of innate immune response; regulation of inflammatory response; immune response; positive regulation of release of sequestered calcium ion into cytosol; negative regulation of transcription, DNA-dependent