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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver cancer using MBS1499706 at dilution 1:100)

Rabbit anti-Human Lymphatic vessel endothelial hyaluronic acid receptor 1 Polyclonal Antibody | anti-LYVE1 antibody

Rabbit anti-human Lymphatic vessel endothelial hyaluronic acid receptor 1 polyclonal Antibody(LYVE1)

Gene Names
LYVE1; HAR; XLKD1; LYVE-1; CRSBP-1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
Lymphatic vessel endothelial hyaluronic acid receptor 1; Polyclonal Antibody; Rabbit anti-human Lymphatic vessel endothelial hyaluronic acid receptor 1 polyclonal Antibody(LYVE1); LYVE-1; Cell surface retention sequence-binding protein 1; CRSBP-1; Extracellular link domain-containing protein 1; Hyaluronic acid receptor; LYVE1; CRSBP1; HAR; XLKD1; UNQ230/PRO263; anti-LYVE1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
322
Applicable Applications for anti-LYVE1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Lymphatic vessel endothelial hyaluronic acid receptor 1 protein (20-238aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-19316 / sc-31289 / sc-31290 / sc-31292 / sc-31293 / sc-28190
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver cancer using MBS1499706 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver cancer using MBS1499706 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer using MBS1499706 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer using MBS1499706 at dilution 1:100)
Related Product Information for anti-LYVE1 antibody
Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,213 Da
NCBI Official Full Name
lymphatic vessel endothelial hyaluronic acid receptor 1
NCBI Official Synonym Full Names
lymphatic vessel endothelial hyaluronan receptor 1
NCBI Official Symbol
LYVE1
NCBI Official Synonym Symbols
HAR; XLKD1; LYVE-1; CRSBP-1
NCBI Protein Information
lymphatic vessel endothelial hyaluronic acid receptor 1
UniProt Protein Name
Lymphatic vessel endothelial hyaluronic acid receptor 1
UniProt Gene Name
LYVE1
UniProt Synonym Gene Names
CRSBP1; HAR; XLKD1; LYVE-1; CRSBP-1
UniProt Entry Name
LYVE1_HUMAN

NCBI Description

This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]

Uniprot Description

XLKD1: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: integral to plasma membrane; membrane; plasma membrane

Molecular Function: hyaluronic acid binding; protein binding; receptor activity; transmembrane receptor activity

Biological Process: anatomical structure morphogenesis; carbohydrate metabolic process; cell motility; cell-matrix adhesion; glycosaminoglycan metabolic process; hyaluronan catabolic process; hyaluronan metabolic process; response to wounding; signal transduction; transport

Research Articles on LYVE1

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Product Notes

The LYVE1 lyve1 (Catalog #AAA1499706) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Lymphatic vessel endothelial hyaluronic acid receptor 1 polyclonal Antibody(LYVE1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lymphatic vessel endothelial hyaluronic acid receptor 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC:1:20-1:200. Researchers should empirically determine the suitability of the LYVE1 lyve1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lymphatic vessel endothelial hyaluronic acid receptor 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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