Western Blot (WB)
(Western Blot analysis of G6D in human platelet lysate in the 1) absence and 2) presence of immunizing peptide using MBS6005610 at 1ug/ml. IgG (HRP) goat anti-rabbit secondary antibody and ECL substrate solution were used for this test.)
Rabbit anti-Human LY6G6D Polyclonal Antibody | anti-LY6G6D antibody
LY6G6D (G6D, Lymphocyte Antigen 6 Complex Locus Protein G6f, C6orf21, G6F, LY6G6D, NG32)
Gene Names
LY6G6D; G6D; NG25; LY6-D; MEGT1; C6orf23
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
LY6G6D; Polyclonal Antibody; LY6G6D (G6D; Lymphocyte Antigen 6 Complex Locus Protein G6f; C6orf21; G6F; NG32); Anti -LY6G6D (G6D; anti-LY6G6D antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human LY6G6D. Species Crossreactivity: chimpanzee.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Concentration
0.5mg/ml (varies by lot)
Applicable Applications for anti-LY6G6D antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1-3ug/ml
Immunohistochemistry (FFPE): 5ug/ml
Optimal dilutions to be determined by the researcher.
Immunohistochemistry (FFPE): 5ug/ml
Optimal dilutions to be determined by the researcher.
Immunogen
Synthetic peptide corresponding to a portion of aa66-100 of human LY6G6D. Species Sequence Homology: Human, chimpanzee: 100%, Mouse, Equine, Rat, Rhesus monkey and Canine: 95%, Bovine: 90%, Platypus: 80%, Opossum: 70%
Preparation and Storage
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of G6D in human platelet lysate in the 1) absence and 2) presence of immunizing peptide using MBS6005610 at 1ug/ml. IgG (HRP) goat anti-rabbit secondary antibody and ECL substrate solution were used for this test.)
Western Blot (WB)
(Western Blot analysis of G6D in human platelet lysate in the 1) absence and 2) presence of immunizing peptide using MBS6005610 at 1ug/ml. IgG (HRP) goat anti-rabbit secondary antibody and ECL substrate solution were used for this test.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of G6D in formalin-fixed, paraffin-embedded human liver tissue using an isotype control (top) and (bottom) MBS6005610 at 5ug/ml.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of G6D in formalin-fixed, paraffin-embedded human liver tissue using an isotype control (top) and (bottom) MBS6005610 at 5ug/ml.)
Related Product Information for anti-LY6G6D antibody
G6D, also known as Lymphocyte antigen 6 complex locus G6D (LY6G6D), is a type I transmembrane protein belonging to the immunoglobin (Ig) superfamily, which is comprised of cell-surface proteins involved in the immune system and cellular recognition. It is a disulfide linked homodimer with an Ig-like V-type domain and is known to interact with GRB2 and GRB7 in a phosphorylation-dependent manner thus playing an important role in their downstream signal transduction pathways.
Product Categories/Family for anti-LY6G6D antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43KD
NCBI Official Full Name
lymphocyte antigen 6 complex locus protein G6d
NCBI Official Synonym Full Names
lymphocyte antigen 6 complex, locus G6D
NCBI Official Symbol
LY6G6D
NCBI Official Synonym Symbols
G6D; NG25; LY6-D; MEGT1; C6orf23
NCBI Protein Information
lymphocyte antigen 6 complex locus protein G6d; protein Ly6-D; lymphocyte antigen-6 G6D; megakaryocyte-enhanced gene transcript 1 protein
UniProt Protein Name
Lymphocyte antigen 6 complex locus protein G6d
Protein Family
UniProt Gene Name
LY6G6D
UniProt Synonym Gene Names
C6orf23; G6D; MEGT1; NG25; Protein Ly6-D
UniProt Entry Name
LY66D_HUMAN
NCBI Description
LY6G6D belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Apr 2009]
Uniprot Description
LY6G6D: Homodimer.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: plasma membrane; filopodium
Research Articles on LY6G6D
Similar Products
Product Notes
The LY6G6D ly6g6d (Catalog #AAA6005610) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LY6G6D (G6D, Lymphocyte Antigen 6 Complex Locus Protein G6f, C6orf21, G6F, LY6G6D, NG32) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LY6G6D can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1-3ug/ml Immunohistochemistry (FFPE): 5ug/ml Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the LY6G6D ly6g6d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LY6G6D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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