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Rabbit anti-Human LST1 Polyclonal Antibody | anti-LST1 antibody

LST1 Antibody

Gene Names
LST1; B144; LST-1; D6S49E
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
LST1; Polyclonal Antibody; LST1 Antibody; B144; B144 protein; D6S49E; Leucocyte specific transcript 1; Leukocyte-specific transcript 1 protein; Liver Specific Transporter; LIVTR; LST 1; Lst1; LST1_HUMAN; lymphocyte antigen 117; MGC119006; MGC119007; OTTHUMP00000029390; OTTHUMP00000029391; OTTHUMP00000029392; OTTHUMP00000029396; OTTHUMP00000029397; OTTHUMP00000029398; OTTHUMP00000038208; OTTHUMP00000038211; OTTHUMP00000038213; OTTHUMP00000038312; OTTHUMP00000038314; OTTHUMP00000038315; OTTHUMP00000038651; OTTHUMP00000038655; OTTHUMP00000038657; OTTHUMP00000166011; OTTHUMP00000166014; OTTHUMP00000166016; OTTHUMP00000166017; OTTHUMP00000166018; OTTHUMP00000166019; OTTHUMP00000215143; Protein B144; anti-LST1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
LST1 Antibody detects endogenous levels of LST1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-LST1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human LST1.
Conjugation
Unconjugated
Similarity
Belongs to the LST1 family.
Tissue Specificity
Expressed in lung, tonsil, thymus, placenta, kidney, fetal spleen, fetal liver and brain.
Function
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
Note
Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
8,350 Da
NCBI Official Full Name
leukocyte-specific transcript 1 protein isoform 6
NCBI Official Synonym Full Names
leukocyte specific transcript 1
NCBI Official Symbol
LST1
NCBI Official Synonym Symbols
B144; LST-1; D6S49E
NCBI Protein Information
leukocyte-specific transcript 1 protein; lymphocyte antigen 117
UniProt Protein Name
Leukocyte-specific transcript 1 protein
UniProt Gene Name
LST1
UniProt Synonym Gene Names
B144
UniProt Entry Name
LST1_HUMAN

NCBI Description

The protein encoded by this gene is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

LST1: Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation. Belongs to the LST1 family. 10 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cytoskeletal

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: Golgi membrane; Golgi apparatus; cytoplasm; integral to membrane

Biological Process: regulation of cell shape; anatomical structure morphogenesis; cell morphogenesis; dendrite development; immune response; negative regulation of lymphocyte proliferation

Research Articles on LST1

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Product Notes

The LST1 lst1 (Catalog #AAA9630839) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LST1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LST1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the LST1 lst1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LST1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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