Rabbit anti-Human LSM7 Polyclonal Antibody | anti-LSM7 antibody

LSM7 Antibody

Cat. Num. AAA7005990

• Gene Names: LSM7; YNL147W
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >95%,Protein G purified
• Synonyms: LSM7; Polyclonal Antibody; LSM7 Antibody; U6 snRNA-associated Sm-like protein LSm7; anti-LSM7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 103

• Applicable Applications for anti-LSM7 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Recombinant human U6 snRNA-associated Sm-like protein LSm7 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82652 / sc-82653
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western blotAll lanes: LSM7 antibody at 3ug/ml+Caco-2 whole cell lysateGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 12 kDaObserved band size: 12 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7005990 at dilution of 1:100)

Related Product Information for anti-LSM7 antibody

Binds specifically to the 3'-terminal U-tract of U6 snRNA and is probably a component of the spliceosome.

NCBI and Uniprot Product Information

• NCBI GI #: 7706423
• NCBI GeneID: 51690
• NCBI Accession #: NP_057283.1
• NCBI GenBank Nucleotide #: NM_016199.2
• UniProt Accession #: Q9UK45
• Molecular Weight: 11,602 Da
• NCBI Official Full Name: U6 snRNA-associated Sm-like protein LSm7
• NCBI Official Synonym Full Names: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
• NCBI Official Symbol: LSM7
• NCBI Official Synonym Symbols: YNL147W
• NCBI Protein Information: U6 snRNA-associated Sm-like protein LSm7
• UniProt Protein Name: U6 snRNA-associated Sm-like protein LSm7
• Protein Family: Sm-like protein
• UniProt Gene Name: LSM7
• UniProt Entry Name: LSM7_HUMAN

NCBI Description

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]

Uniprot Description

LSM7: Binds specifically to the 3'-terminal U-tract of U6 snRNA. Belongs to the snRNP Sm proteins family.

Protein type: Spliceosome; RNA splicing

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytosol; nucleoplasm; small nucleolar ribonucleoprotein complex; U12-dependent spliceosome

Molecular Function: protein binding; RNA binding; U6 snRNA binding

Biological Process: gene expression; mRNA catabolic process, deadenylation-dependent decay; nuclear mRNA splicing, via spliceosome; RNA processing; RNA splicing