Immunohistochemistry (IHC)
(Anti-LRPAP1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.)
Rabbit anti-Human LRPAP1 Polyclonal Antibody | anti-LRPAP1 antibody
Rabbit Polyclonal (IgG) to Human LRPAP1
Usage: Suggested starting dilutions are as follows: Western blot: 1:500-1:3000. IHC-Paraffin: 7.5 ug/ml. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Immunohistochemistry (IHC)
(Anti-LRPAP1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-LRPAP1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.)
Western Blot (WB)
(Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 10% SDS PAGE LRPAP1 antibody diluted at 1:1000)
Western Blot (WB)
(Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 10% SDS PAGE LRPAP1 antibody diluted at 1:1000)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands. Mutations in this gene have been identified in individuals with myopia 23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
LRPAP1: Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis. Belongs to the alpha-2-MRAP family.
Protein type: Receptor, misc.
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: cell surface; endoplasmic reticulum; integral to membrane; extracellular region; plasma membrane; vesicle
Molecular Function: heparin binding; protein binding; receptor antagonist activity; low-density lipoprotein receptor binding; unfolded protein binding; asialoglycoprotein receptor activity
Biological Process: vesicle-mediated transport; receptor-mediated endocytosis; protein folding; negative regulation of protein binding
Disease: Myopia 23, Autosomal Recessive
Research Articles on LRPAP1
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Product Notes
The LRPAP1 lrpap1 (Catalog #AAA248005) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human LRPAP1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRPAP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (7.5 ug/ml), WB (1:500 - 1:3000) Usage: Suggested starting dilutions are as follows: Western blot: 1:500-1:3000. IHC-Paraffin: 7.5 ug/ml. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. Researchers should empirically determine the suitability of the LRPAP1 lrpap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRPAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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