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Immunocytochemistry (ICC) (Immunocytochemistry Analysis: Representative lot data. Confocal fluorescent analysis of non-transfected CHEM1 cells, CHEM1 cells transfected with LPA receptor 5, and TF1 cells using Anti-LPA receptor 5 (GPR92) and a Donkey Anti-Rabbit secondary antibody conjugated to Cy3 (Red). Actin filaments have been labeled with Alexa Fluor 488 dye-Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains the cytoplasm. NOTE: The protein used to make the transfected CHEM1 cell line is full length LPAR5.)

Rabbit anti-Human, Mouse LPAR5 Polyclonal Antibody | anti-LPAR5 antibody

LPAR5 (Lysophosphatidic Acid Receptor 5, LPA Receptor 5, LPA-5, G-protein Coupled Receptor 92, G-protein Coupled Receptor 93, GPR92, GPR93) (MaxLight 490)

Gene Names
LPAR5; LPA5; GPR92; GPR93; KPG_010
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot
Purity
Purified by Immunoaffinity chromatography.
Synonyms
LPAR5; Polyclonal Antibody; LPAR5 (Lysophosphatidic Acid Receptor 5; LPA Receptor 5; LPA-5; G-protein Coupled Receptor 92; G-protein Coupled Receptor 93; GPR92; GPR93) (MaxLight 490); anti-LPAR5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes the extracellular domain of human LPA receptor 5. Species Crossreactivity: mouse.
Purity/Purification
Purified by Immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Applicable Applications for anti-LPAR5 antibody
Immunocytochemistry (ICC), Western Blot (WB)
Application Notes
ICC: 1:500
Applications are based on unconjugated antibody.
Immunogen
Linear peptide corresponding to the extracellular domain of human LPA receptor 5, conjugated to KLH.
Conjugate
MaxLight490
Control
K562 cell lysate
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Immunocytochemistry (ICC)

(Immunocytochemistry Analysis: Representative lot data. Confocal fluorescent analysis of non-transfected CHEM1 cells, CHEM1 cells transfected with LPA receptor 5, and TF1 cells using Anti-LPA receptor 5 (GPR92) and a Donkey Anti-Rabbit secondary antibody conjugated to Cy3 (Red). Actin filaments have been labeled with Alexa Fluor 488 dye-Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains the cytoplasm. NOTE: The protein used to make the transfected CHEM1 cell line is full length LPAR5.)

Immunocytochemistry (ICC) (Immunocytochemistry Analysis: Representative lot data. Confocal fluorescent analysis of non-transfected CHEM1 cells, CHEM1 cells transfected with LPA receptor 5, and TF1 cells using Anti-LPA receptor 5 (GPR92) and a Donkey Anti-Rabbit secondary antibody conjugated to Cy3 (Red). Actin filaments have been labeled with Alexa Fluor 488 dye-Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains the cytoplasm. NOTE: The protein used to make the transfected CHEM1 cell line is full length LPAR5.)

Western Blot (WB)

(Western Blotting Analysis: Representative lot data. K562 cell lysate was probed withnti-LPA receptor 5 (GPR92) (0.2ug/ml). Proteins were visualized using a Donkey Anti-Rabbit IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates LPA Receptor 5 (~37kD).)

Western Blot (WB) (Western Blotting Analysis: Representative lot data. K562 cell lysate was probed withnti-LPA receptor 5 (GPR92) (0.2ug/ml). Proteins were visualized using a Donkey Anti-Rabbit IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates LPA Receptor 5 (~37kD).)
Product Categories/Family for anti-LPAR5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41kDa
NCBI Official Full Name
lysophosphatidic acid receptor 5
NCBI Official Synonym Full Names
lysophosphatidic acid receptor 5
NCBI Official Symbol
LPAR5
NCBI Official Synonym Symbols
LPA5; GPR92; GPR93; KPG_010
NCBI Protein Information
lysophosphatidic acid receptor 5
UniProt Protein Name
Lysophosphatidic acid receptor 5
UniProt Gene Name
LPAR5
UniProt Synonym Gene Names
GPR92; GPR93; LPA receptor 5; LPA-5
UniProt Entry Name
LPAR5_HUMAN

NCBI Description

This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]

Uniprot Description

GPR92: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on LPAR5

Similar Products

Product Notes

The LPAR5 lpar5 (Catalog #AAA6444716) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LPAR5 (Lysophosphatidic Acid Receptor 5, LPA Receptor 5, LPA-5, G-protein Coupled Receptor 92, G-protein Coupled Receptor 93, GPR92, GPR93) (MaxLight 490) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LPAR5 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Western Blot (WB). ICC: 1:500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the LPAR5 lpar5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LPAR5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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