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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using MBS7128296(LPAR3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Rabbit LPAR3 Polyclonal Antibody | anti-LPAR3 antibody

LPAR3 Antibody

Gene Names
LPAR3; EDG7; GPCR; LPA3; Edg-7; LP-A3; HOFNH30; RP4-678I3
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
LPAR3; Polyclonal Antibody; LPAR3 Antibody; lysophosphatidic acid receptor 3; anti-LPAR3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-LPAR3 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:10000
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human LPAR3
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using MBS7128296(LPAR3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using MBS7128296(LPAR3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7128296(LPAR3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7128296(LPAR3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))
Product Categories/Family for anti-LPAR3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,128 Da
NCBI Official Full Name
lysophosphatidic acid receptor 3
NCBI Official Synonym Full Names
lysophosphatidic acid receptor 3
NCBI Official Symbol
LPAR3
NCBI Official Synonym Symbols
EDG7; GPCR; LPA3; Edg-7; LP-A3; HOFNH30; RP4-678I3
NCBI Protein Information
lysophosphatidic acid receptor 3; LPA-3; LPA receptor 3; LPA receptor EDG7; lysophosphatidic acid receptor Edg-7; endothelial cell differentiation gene 7; calcium-mobilizing lysophosphatidic acid receptor LP-A3; endothelial differentiation, lysophosphatid
UniProt Protein Name
Lysophosphatidic acid receptor 3
UniProt Gene Name
LPAR3
UniProt Synonym Gene Names
EDG7; LPA3; LPA receptor 3; LPA-3
UniProt Entry Name
LPAR3_HUMAN

NCBI Description

This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. [provided by RefSeq, Jul 2008]

Uniprot Description

EDG7: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1p22.3

Cellular Component: axon; integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; phospholipid binding; G-protein alpha-subunit binding; lipid binding

Biological Process: synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); activation of MAPK activity; bleb formation; positive regulation of calcium ion transport; positive regulation of collateral sprouting

Research Articles on LPAR3

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Product Notes

The LPAR3 lpar3 (Catalog #AAA7128296) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LPAR3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LPAR3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:2000-1:10000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the LPAR3 lpar3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LPAR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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