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Testing Data

Rabbit LOXHD1 Polyclonal Antibody | anti-LOXHD1 antibody

LOXHD1 Antibody

Gene Names
LOXHD1; LH2D1; DFNB77
Reactivity
Human
Predicted: Mouse, Rat
Not yet tested in other species
Applications
ELISA, Western Blot
Synonyms
LOXHD1; Polyclonal Antibody; LOXHD1 Antibody; anti-LOXHD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Not yet tested in other species
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3.
Sequence Length
1011
Applicable Applications for anti-LOXHD1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20,000 - 1:80,000
WB: 1:500 - 1:1000
Optimal dilutions should be determined by the end user
Preparation and Storage
Already reconstituted in 200ul sterile H2O.
The antibody is stable for at least one year when stored at -20°C after reconstitution.
Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data
Related Product Information for anti-LOXHD1 antibody
Rabbit polyclonal LOXHD1 (1) antibody was raised against a recombinated human LOXHD1 protein 249-444aa (BC041860).
References
(1) Strausberg, R.L., Feingold, E.A., Grouse, L.H. et al. Generation and initial analysis of more than 15, 000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
lipoxygenase homology domain-containing protein 1 isoform 5
NCBI Official Synonym Full Names
lipoxygenase homology domains 1
NCBI Official Symbol
LOXHD1
NCBI Official Synonym Symbols
LH2D1; DFNB77
NCBI Protein Information
lipoxygenase homology domain-containing protein 1
UniProt Protein Name
Lipoxygenase homology domain-containing protein 1
UniProt Gene Name
LOXHD1

NCBI Description

This gene encodes a highly conserved protein consisting entirely of PLAT (polycystin/lipoxygenase/alpha-toxin) domains, thought to be involved in targeting proteins to the plasma membrane. Studies in mice show that this gene is expressed in the mechanosensory hair cells in the inner ear, and mutations in this gene lead to auditory defects, indicating that this gene is essential for normal hair cell function. Screening of human families segregating deafness identified a mutation in this gene which causes DFNB77, a progressive form of autosomal-recessive nonsyndromic hearing loss (ARNSHL). Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2010]

Uniprot Description

Involved in hearing. Required for normal function of hair cells in the inner ear ().

Research Articles on LOXHD1

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Product Notes

The LOXHD1 loxhd1 (Catalog #AAA8527008) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LOXHD1 Antibody reacts with Human Predicted: Mouse, Rat
Not yet tested in other species and may cross-react with other species as described in the data sheet. AAA Biotech's LOXHD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20,000 - 1:80,000 WB: 1:500 - 1:1000 Optimal dilutions should be determined by the end user. Researchers should empirically determine the suitability of the LOXHD1 loxhd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LOXHD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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