Testing Data
Rabbit FBXO10 Polyclonal Antibody | anti-FBXO10 antibody
FBXO10 Antibody
Gene Names
FBXO10; FBX10; PRMT11
Reactivity
Reacts with: HumanPredicted: Rat, Mouse
Not yet tested in other species.
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
FBXO10; Polyclonal Antibody; FBXO10 Antibody; anti-FBXO10 antibody
Host
Rabbit
Reactivity
Reacts with: Human
Predicted: Rat, Mouse
Not yet tested in other species.
Predicted: Rat, Mouse
Not yet tested in other species.
Clonality
Polyclonal
Form/Format
Lyophilized FBXO10 antibody purified by protein affinity column containing 1% BSA and 0.02% NaN3.
Sequence Length
2999
Applicable Applications for anti-FBXO10 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:1,000-1:2,000
IHC: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.
WB: 1:1,000-1:2,000
IHC: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.
Source Note
Rabbit polyclonal FBXO10 (1) antibody was raised against a recombinated human FBXO10 protein 11-179aa (BC125125).
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for anti-FBXO10 antibody
Rabbit polyclonal FBXO10 (1) antibody was raised against a recombinated human FBXO10 protein 11-179aa (BC125125).
Product Categories/Family for anti-FBXO10 antibody
References
(1) Barnholtz-Sloan, J.S., Shetty, P.B., Guan, X., et al. FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women. Carcinogenesis 31 (8), 1417-1423 (2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Homo sapiens F-box protein 10, mRNA
NCBI Official Synonym Full Names
F-box protein 10
NCBI Official Symbol
FBXO10
NCBI Official Synonym Symbols
FBX10; PRMT11
NCBI Protein Information
F-box only protein 10
UniProt Protein Name
F-box only protein 10
Protein Family
UniProt Gene Name
FBXO10
UniProt Synonym Gene Names
FBX10; PRMT11
NCBI Description
Members of the F-box protein family, such as FBXO10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Uniprot Description
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The SCF(FBXO10) complex mediates ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2.
Research Articles on FBXO10
Similar Products
Product Notes
The FBXO10 fbxo10 (Catalog #AAA859343) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FBXO10 Antibody reacts with Reacts with: Human Predicted: Rat, Mouse Not yet tested in other species. and may cross-react with other species as described in the data sheet. AAA Biotech's FBXO10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:1,000-1:2,000 IHC: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the FBXO10 fbxo10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBXO10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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