Rabbit anti-Human LNX2 Polyclonal Antibody | anti-LNX2 antibody

LNX2

Cat. Num. AAA395447

• Gene Names: LNX2; PDZRN1
• Reactivity: Human
• Applications: Western Blot
• Purity: Ammonium Sulfate Precipitation
• Synonyms: LNX2; Polyclonal Antibody; Numb-binding protein 2; PDZ domain-containing RING finger protein 1; anti-LNX2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Ammonium Sulfate Precipitation
• Form/Format: Provided as solution in phosphate buffered saline with 0.08% sodium azide
• Sequence Length: 690

• Applicable Applications for anti-LNX2 antibody: Western Blot (WB)
• Immunogen: Synthetic peptide derived from human LNX2 protein
• Positive Control: Protein found in colon and in developing and adult brain.
• Preparation and Storage: Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles

Related Product Information for anti-LNX2 antibody

Interacts with the phosphotyrosine interaction domain of Numb. Lnx proteins may server as molecular scaffolds that localize unrelated, interacting proteins, such as Numb, to specific subcellular sites. Forms oligomers via their PDZ binding domains to PDZ-binding consensus motifs located in their C-termini or by homophilic oligomerization of their RING fingers.

Product Categories/Family for anti-LNX2 antibody

Polyclonal Antibody

NCBI and Uniprot Product Information

• NCBI GI #: 24025688
• NCBI GeneID: 222484
• NCBI Accession #: NP_699202.1
• NCBI GenBank Nucleotide #: NM_153371.3
• UniProt Accession #: Q8N448; Q5W0P0; Q6ZMH2; Q96SH4
• Molecular Weight: 76 kDa
• NCBI Official Full Name: ligand of Numb protein X 2
• NCBI Official Synonym Full Names: ligand of numb-protein X 2
• NCBI Official Symbol: LNX2
• NCBI Official Synonym Symbols: PDZRN1
• NCBI Protein Information: ligand of Numb protein X 2; numb-binding protein 2; PDZ domain containing ring finger 1; PDZ domain-containing RING finger protein 1
• UniProt Protein Name: Ligand of Numb protein X 2
• Protein Family: Ligand of Numb protein
• UniProt Gene Name: LNX2
• UniProt Synonym Gene Names: PDZRN1
• UniProt Entry Name: LNX2_HUMAN

Uniprot Description

Subunit structure: Interacts with the phosphotyrosine interaction domain of NUMB

By similarity.

Domain: The NPXY motif is required for the interaction with the PID domain of NUMB. It is however not sufficient.

Sequence similarities: Contains 4 PDZ (DHR) domains.Contains 1 RING-type zinc finger.

Sequence caution: The sequence BAD18754.1 differs from that shown. Reason: Erroneous initiation.