Western Blot (WB)
(Host: RabbitTarget Name: LMOD3Sample Type: HCT15 Whole Cell lysatesAntibody Dilution: 1.0ug/ml)
Rabbit LMOD3 Polyclonal Antibody | anti-LMOD3 antibody
LMOD3 Antibody - N-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: LMOD3Sample Type: HCT15 Whole Cell lysatesAntibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: LMOD3Sample Type: HCT15 Whole Cell lysatesAntibody Dilution: 1.0ug/ml)
Target Description: The function of this protein remains unknown.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the leiomodin family of proteins. This protein contains three actin-binding domains, a tropomyosin domain, a leucine-rich repeat domain, and a Wiskott-Aldrich syndrome protein homology 2 domain (WH2). Localization of this protein to the pointed ends of thin filaments has been observed, and there is evidence that this protein acts as a catalyst of actin nucleation, and is important to the organization of sarcomeric thin filaments in skeletal muscles. Mutations in this gene have been associated as one cause of Nemaline myopathy, as other genes have also been linked to this disorder. Nemaline myopathy is a disorder characterized by nonprogressive generalized muscle weakness and protein inclusions (nemaline bodies) in skeletal myofibers. Patients with mutations in this gene often present with a severe congenital form of the disorder. [provided by RefSeq, Jan 2015]
Uniprot Description
Essential for the organization of sarcomeric actin thin filaments in skeletal muscle (PubMed:25250574). Increases the rate of actin polymerization (PubMed:25250574).
Research Articles on LMOD3
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Product Notes
The LMOD3 lmod3 (Catalog #AAA3218610) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LMOD3 Antibody - N-terminal region reacts with Cow, Dog, Horse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's LMOD3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the LMOD3 lmod3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: VKSEEKTQEE HEEIEKRNKN MAQYLKEKLN NEIVANKRES KGSSNIQETD. It is sometimes possible for the material contained within the vial of "LMOD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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