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Western Blot (WB) (Western blot analysis of LMOD1 Antibody (Center N201) in Hela cell line lysates (35ug/lane). LMOD1 (arrow) was detected using the purified Pab.)

Rabbit anti-Human LMOD1 Polyclonal Antibody | anti-LMOD1 antibody

LMOD1 (Leiomodin 1, Leiomodin-1, 64kD Autoantigen 1D, 64kD Autoantigen 1D3, 64kD Autoantigen D1, FLJ55689, Leiomodin Muscle Form, Smooth Muscle Leiomodin, SM-Lmod, Thyroid-associated Ophthalmopathy Autoantigen) (FITC)

Gene Names
LMOD1; 1D; D1; 64kD; SMLMOD; SM-LMOD
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
LMOD1; Polyclonal Antibody; LMOD1 (Leiomodin 1; Leiomodin-1; 64kD Autoantigen 1D; 64kD Autoantigen 1D3; 64kD Autoantigen D1; FLJ55689; Leiomodin Muscle Form; Smooth Muscle Leiomodin; SM-Lmod; Thyroid-associated Ophthalmopathy Autoantigen) (FITC); Leiomodin 1 (Smooth Muscle); anti-LMOD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human LMOD.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-LMOD1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:50-1:100
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the center region of human LMOD (KLH).
Conjugate
FITC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.

Western Blot (WB)

(Western blot analysis of LMOD1 Antibody (Center N201) in Hela cell line lysates (35ug/lane). LMOD1 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of LMOD1 Antibody (Center N201) in Hela cell line lysates (35ug/lane). LMOD1 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human skeletal muscle reacted with LMOD1 Antibody (Center N201), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human skeletal muscle reacted with LMOD1 Antibody (Center N201), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of hela cells using LMOD1 Antibody (Center N201)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of hela cells using LMOD1 Antibody (Center N201)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-LMOD1 antibody
References
1. Zhang, Z.G., et.al., Clin. Immunol. Immunopathol. 80(3 PT 1), 236-244 (1996). 2. Conley, C.A.et.al., Curr. Eye Res. 19(4), 313-322 (1999).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67kDa
NCBI Official Full Name
leiomodin-1
NCBI Official Synonym Full Names
leiomodin 1
NCBI Official Symbol
LMOD1
NCBI Official Synonym Symbols
1D; D1; 64kD; SMLMOD; SM-LMOD
NCBI Protein Information
leiomodin-1
UniProt Protein Name
Leiomodin-1
Protein Family
UniProt Gene Name
LMOD1
UniProt Synonym Gene Names
SM-Lmod
UniProt Entry Name
LMOD1_HUMAN

NCBI Description

The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008]

Uniprot Description

LMOD1: The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: membrane; cytosol; striated muscle thin filament

Molecular Function: actin binding; tropomyosin binding

Biological Process: myofibril assembly; muscle contraction; actin filament organization; pointed-end actin filament capping

Research Articles on LMOD1

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Product Notes

The LMOD1 lmod1 (Catalog #AAA6485366) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LMOD1 (Leiomodin 1, Leiomodin-1, 64kD Autoantigen 1D, 64kD Autoantigen 1D3, 64kD Autoantigen D1, FLJ55689, Leiomodin Muscle Form, Smooth Muscle Leiomodin, SM-Lmod, Thyroid-associated Ophthalmopathy Autoantigen) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LMOD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:50-1:100 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the LMOD1 lmod1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LMOD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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