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Rabbit anti-Murine LIX LIX Polyclonal Antibody | anti-LIX antibody

LIX antibody

Gene Names
Cxcl5; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II
Reactivity
Murine LIX
Applications
ELISA, Western Blot
Synonyms
LIX; Polyclonal Antibody; LIX antibody; Polyclonal LIX; Anti-LIX; ENA-78; CXCL5; anti-LIX antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Murine LIX
Clonality
Polyclonal
Specificity
Murine LIX
Form/Format
Lyophilized from PBS, pH 7.2.
Sequence Length
132
Applicable Applications for anti-LIX antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Biological Significance
The Mouse homolog of ENA-78 is called LIX. LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ?ELR? motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors.
Immunogen
LIX antibody was raised in rabbit using highly pure recombinant murine LIX as the immunogen.
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-LIX antibody
Affinity purified Rabbit polyclonal LIX antibody
Product Categories/Family for anti-LIX antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
7.6 kDa (predicted detection band MW)
NCBI Official Full Name
LIX
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 5
NCBI Official Symbol
Cxcl5
NCBI Official Synonym Symbols
LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II
NCBI Protein Information
C-X-C motif chemokine 5
UniProt Protein Name
C-X-C motif chemokine 5
Protein Family
UniProt Gene Name
Cxcl5
UniProt Synonym Gene Names
Scyb5
UniProt Entry Name
CXCL5_MOUSE

NCBI Description

This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils and to have homeostatic and inflammatory functions. In mouse, deficiency of this gene is associated with increased lung inflammation that is neutrophil-dependent. [provided by RefSeq, May 2013]

Uniprot Description

CXCL6: Chemotactic for neutrophil granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; CXCR chemokine receptor binding; cytokine activity

Biological Process: G-protein coupled receptor protein signaling pathway; organ regeneration; cytokine production; positive regulation of JAK-STAT cascade; response to lipopolysaccharide; immune response; positive regulation of leukocyte chemotaxis; chemotaxis; inflammatory response; regulation of chemokine production; regulation of cell proliferation; leukocyte homeostasis

Research Articles on LIX

Similar Products

Product Notes

The LIX cxcl5 (Catalog #AAA535735) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LIX antibody reacts with Murine LIX and may cross-react with other species as described in the data sheet. AAA Biotech's LIX can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). Researchers should empirically determine the suitability of the LIX cxcl5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LIX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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