Rabbit liver FABP Polyclonal Antibody | anti-FABP1 antibody

Anti-liver FABP antibody

Cat. Num. AAA176824

• Gene Names: FABP1; FABPL; L-FABP
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Immunogen affinity purified.
• Synonyms: liver FABP; Polyclonal Antibody; Anti-liver FABP antibody; Fatty acid-binding protein; liver; fatty acid binding protein 1; FABP 1 antibody; FABP1 antibody; FABP-1 antibody; FABPL antibody; FABPL_HUMAN antibody; Fatty Acid Binding Protein 1 antibody; Fatty acid binding protein 1 liver antibody; Fatty Acid Binding Protein antibody; Fatty acid-binding protein 1 antibody; Fatty acid-binding protein antibody; Fatty acid-binding protein liver antibody; L FABP antibody; L-FABP antibody; liver antibody; Liver-type fatty acid-binding protein antibody; anti-FABP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Immunogen affinity purified.
• Form/Format: Lyophilized
• Sequence Length: 127

• Applicable Applications for anti-FABP1 antibody: Western Blot (WB), Immunohistochemistry (IHC) Paraffin
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human liver FABP (16-31aa EAFMKAIGLPEELIQK), different from the related mouse sequence by two amino acids.
• Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
• Preparation and Storage: At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Western Blot (WB)

(Anti-liver FABP antibody, MBS176824, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Rat Kidney Tissue LysateLane 3: HELA Cell LysateLane 4: NEURO Cell LysateLane 5: SMMC Cell Lysate )

Immunohistochemistry (IHC)

(Anti-liver FABP antibody, MBS176824, IHC(P)IHC(P): Rat Liver Tissue )

Immunohistochemistry (IHC)

(Anti-liver FABP antibody, MBS176824, IHC(P)IHC(P): Human Liver Cancer Tissue )

Related Product Information for anti-FABP1 antibody

Description: Rabbit IgG polyclonal antibody for Fatty acid-binding protein, liver(FABP1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: Fatty acid binding protein 1, liver, also known as FABP1 or FABPL, is a human gene locating at 2p11. FABP1 encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind free fatty acids, their CoA derivatives, bilirubin, organic anions, and other small molecules. FABP1 and FABP6(the ileal fatty acid binding protein) are also able to bind bile acids. It is though that FABPs roles include fatty acid uptake, transport, and metaboism. The liver form of FABP may be identical to the major liver protein-1(Lvp-1), which is encoded by a gene situated within 1 cM of Ly-2.

NCBI and Uniprot Product Information

• NCBI GI #: 119808
• NCBI GeneID: 2168
• UniProt Accession #: P07148
• Molecular Weight: 14,208 Da
• NCBI Official Full Name: Fatty acid-binding protein, liver
• NCBI Official Synonym Full Names: fatty acid binding protein 1, liver
• NCBI Official Symbol: FABP1
• NCBI Official Synonym Symbols: FABPL; L-FABP
• NCBI Protein Information: fatty acid-binding protein, liver; fatty acid-binding protein 1; liver-type fatty acid-binding protein
• UniProt Protein Name: Fatty acid-binding protein, liver
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP1
• UniProt Synonym Gene Names: FABPL; L-FABP
• UniProt Entry Name: FABPL_HUMAN

NCBI Description

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]

Uniprot Description

FABP1: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2p11

Cellular Component: nucleoplasm; peroxisomal matrix; apical cortex; cytosol

Molecular Function: antioxidant activity; bile acid binding; phospholipid binding; chromatin binding; long-chain fatty acid transporter activity; drug binding; fatty acid binding

Biological Process: long-chain fatty acid transport; positive regulation of hydrolase activity; positive regulation of cell proliferation; negative regulation of caspase activity; cellular lipid metabolic process; positive regulation of fatty acid beta-oxidation; intestinal absorption; negative regulation of apoptosis