Rabbit LIS Polyclonal Antibody | anti-LIS antibody

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) LIS Polyclonal Antibody

• Gene Names: LIS; EMB2776; LACHESIS; T26J13.9; T26J13_9
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: LIS; Polyclonal Antibody; Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) LIS Polyclonal Antibody; LIS Antibody; U4/U6 small nuclear ribonucleoprotein PRP4-like protein; Protein EMBRYO DEFECTIVE 2776; Protein LACHESIS; LIS EMB2776 At2g41500 T26J13.9 T32G6.2; anti-LIS antibody

• Host: Rabbit
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-LIS antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Arabidopsis thaliana LIS protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 1063706475
• NCBI GeneID: 818748
• NCBI Accession #: NP_001324961.1
• NCBI GenBank Nucleotide #: NM_001336916.1
• UniProt Accession #: O22212; Q0WNB5; Q7GAP3; Q7Y1Z3
• Molecular Weight: 61,842 Da
• NCBI Official Full Name: WD-40 repeat family protein / small nuclear ribonucleoprotein Prp4p-like protein
• NCBI Official Symbol: LIS
• NCBI Official Synonym Symbols: EMB2776; LACHESIS; T26J13.9; T26J13_9
• NCBI Protein Information: WD-40 repeat family protein / small nuclear ribonucleoprotein Prp4p-like protein
• UniProt Protein Name: U4/U6 small nuclear ribonucleoprotein PRP4-like protein
• Protein Family: Lissencephaly
• UniProt Gene Name: LIS

NCBI Description

Encodes LACHESIS (LIS), a protein with seven WD40 repeats. LIS is homologous to the yeast splicing factor PRP4 which is associated with the U4/U6 complex of the spliceosome. LIS is involved in a mechanism that prevents accessory cells from adopting gametic cell fate: lis mutant forms supernumerary egg cells.

Uniprot Description

Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (). Essential for reproduction. In female gametophyte, is necessary for the egg cell and central cell fate determination and hence reproductive success. Involved in a mechanism that prevents accessory cells from adopting gametic cell fate (PubMed:17326723). Modulates egg cell signaling center that regulates the development of all female gametophytic cells (PubMed:22190635).