Rabbit LIN41 Polyclonal Antibody | anti-LIN41 antibody

LIN41 Rabbit Polyclonal

Cat. Num. AAA7601020

• Gene Names: TRIM71; LIN41; LIN-41
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: LIN41; Polyclonal Antibody; LIN41 Rabbit Polyclonal; anti-LIN41 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 868

• Applicable Applications for anti-LIN41 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Tripartite motif-containing 71
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis using MBS7601020 (LIN41 antibody) at dilution of 1:50)

Western Blot (WB)

(mouse kidney tissue were subjected to SDS PAGE followed by western blot with MBS7601020 (LIN41 antibody) at dilution of 1:300)

NCBI and Uniprot Product Information

• NCBI GI #: 78068056
• NCBI GeneID: 131405
• Molecular Weight: 93,385 Da
• NCBI Official Full Name: LIN41
• NCBI Official Synonym Full Names: tripartite motif containing 71, E3 ubiquitin protein ligase
• NCBI Official Symbol: TRIM71
• NCBI Official Synonym Symbols: LIN41; LIN-41
• NCBI Protein Information: E3 ubiquitin-protein ligase TRIM71
• UniProt Protein Name: E3 ubiquitin-protein ligase TRIM71
• UniProt Gene Name: TRIM71
• UniProt Synonym Gene Names: LIN41
• UniProt Entry Name: LIN41_HUMAN

NCBI Description

The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase transition of the cell cycle. [provided by RefSeq, Dec 2015]

Uniprot Description

TRIM71: May be involved in controlling the timing of organ formation during development. Belongs to the TRIM/RBCC family.

Chromosomal Location of Human Ortholog: 3p22.3

Molecular Function: ligase activity; miRNA binding; translation repressor activity; ubiquitin-protein ligase activity; zinc ion binding

Biological Process: fibroblast growth factor receptor signaling pathway; G1/S transition of mitotic cell cycle; miRNA-mediated gene silencing, negative regulation of translation; negative regulation of translation; neural tube closure; neural tube development; protein autoubiquitination