Rabbit anti-Human, Rat LIMS2 Polyclonal Antibody | anti-LIMS2 antibody
LIMS2 Polyclonal Conjugated Antibody
Gene Names
LIMS2; LGMD2W; PINCH2; MDRCMTT; PINCH-2
Reactivity
Human, Rat
Applications
Most Applications
Purity
Affinity purification
Synonyms
LIMS2; Polyclonal Antibody; LIMS2 Polyclonal Conjugated Antibody; LIMS2 Conjugated Antibody; LGMD2W; PINCH-2; PINCH2; LIM zinc finger domain containing 2; anti-LIMS2 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Sequence Length
341
Applicable Applications for anti-LIMS2 antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
Recombinant fusion protein of human LIMS2 (NP_001154875.1).
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
Related Product Information for anti-LIMS2 antibody
This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39kDa
NCBI Official Full Name
LIM and senescent cell antigen-like-containing domain protein 2 isoform 3
NCBI Official Synonym Full Names
LIM zinc finger domain containing 2
NCBI Official Symbol
LIMS2
NCBI Official Synonym Symbols
LGMD2W; PINCH2; MDRCMTT; PINCH-2
NCBI Protein Information
LIM and senescent cell antigen-like-containing domain protein 2
UniProt Protein Name
LIM and senescent cell antigen-like-containing domain protein 2
UniProt Gene Name
LIMS2
UniProt Synonym Gene Names
PINCH2; PINCH-2
UniProt Entry Name
LIMS2_HUMAN
NCBI Description
This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Uniprot Description
LIMS2: Competes with LIMS1 for binding to ILK. Plays a role in modulating cell spreading and migration. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 2q14.3
Cellular Component: focal adhesion; plasma membrane; nucleus; cytosol
Molecular Function: zinc ion binding
Biological Process: intercellular junction assembly and maintenance; cell-cell adhesion; negative regulation of apoptosis
Research Articles on LIMS2
Similar Products
Product Notes
The LIMS2 lims2 (Catalog #AAA9439847) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LIMS2 Polyclonal Conjugated Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LIMS2 can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the LIMS2 lims2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LIMS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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