Western Blot (WB)
(LHFPL5 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the LHFPL5 antibody detected the LHFPL5 protein (arrow).)
Rabbit LHFPL5 Polyclonal Antibody | anti-LHFPL5 antibody
LHFPL5 Antibody (C-term)
Western Blot (WB)
(LHFPL5 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the LHFPL5 antibody detected the LHFPL5 protein (arrow).)
Western Blot (WB)
(LHFPL5 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the LHFPL5 antibody detected the LHFPL5 protein (arrow).)
(LHFP) gene family, which is a subset of the superfamily of
tetraspan transmembrane protein encoding genes. Mutations in this
gene result in deafness in humans, and a mutation in a similar gene
in mice results in deafness and vestibular dysfunction with severe
degeneration of the organ of Corti. It is proposed to function in
hair bundle morphogenesis.
Shabbir, M.I., et al. J. Med. Genet. 43(8):634-640(2006)
Longo-Guess, C.M., et al. Proc. Natl. Acad. Sci. U.S.A. 102(22):7894-7899(2005)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in this gene result in deafness in humans, and a mutation in a similar gene in mice results in deafness and vestibular dysfunction with severe degeneration of the organ of Corti. It is proposed to function in hair bundle morphogenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
LHFPL5: May function in hair bundle morphogenesis. Defects in LHFPL5 are a cause of deafness autosomal recessive type 67 (DFNB67). DFNB67 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Belongs to the LHFP family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 6p21.31
Cellular Component: apical plasma membrane; integral to membrane; stereocilium bundle tip
Biological Process: ion transport; auditory receptor cell stereocilium organization and biogenesis; detection of mechanical stimulus involved in sensory perception of sound
Disease: Deafness, Autosomal Recessive 67
Research Articles on LHFPL5
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Product Notes
The LHFPL5 lhfpl5 (Catalog #AAA9214489) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 186-214. The LHFPL5 Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's LHFPL5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the LHFPL5 lhfpl5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LHFPL5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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