Rabbit anti-Human LGALS7 Polyclonal Antibody | anti-LGALS7 antibody

LGALS7, ID (LGALS7, PIG1, Galectin-7, HKL-14, PI7, p53-induced gene 1 protein) (PE)

Cat. Num. AAA6315832

• Gene Names: LGALS7B; PI7; GAL7; Gal-7; HKL-14; LGALS7
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LGALS7; Polyclonal Antibody; ID (LGALS7; PIG1; Galectin-7; HKL-14; PI7; p53-induced gene 1 protein) (PE); p53-induced gene 1 protein; anti-LGALS7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-LGALS7 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LGALS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the Central region of human LGALS7.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(LGALS7 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the LGALS7 antibody detected the LGALS7 protein (arrow).)

Product Categories/Family for anti-LGALS7 antibody

Antibodies; Lectins

References

Demers, M., et al. Am. J. Pathol. 176(6):3023-3031(2010). Zhu, X., et al. BMC Cancer 10, 290 (2010): Park, J.E., et al. Oncol. Rep. 22(6):1373-1379(2009). Demers, M., et al. Biochem. Biophys. Res. Commun. 387(3):425-429(2009). Saussez, S., et al. Int. J. Oncol. 34(2):433-439(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 109948279
• NCBI GeneID: 653499
• NCBI Accession #: NP_001035972.1; NP_002298.1
• NCBI GenBank Nucleotide #: NM_001042507.3
• UniProt Accession #: P47929; Q6IB87
• Molecular Weight: 15,075 Da
• NCBI Official Full Name: galectin-7
• NCBI Official Synonym Full Names: lectin, galactoside-binding, soluble, 7B
• NCBI Official Symbol: LGALS7B
• NCBI Official Synonym Symbols: PI7; GAL7; Gal-7; HKL-14; LGALS7
• NCBI Protein Information: galectin-7; galectin 7B; galectin-7B; p53-induced protein 1; keratinocyte lectin 14; p53-induced gene 1 protein; lectin galactoside-binding soluble 7
• UniProt Protein Name: Galectin-7
• Protein Family: Galectin
• UniProt Gene Name: LGALS7
• UniProt Synonym Gene Names: PIG1; Gal-7
• UniProt Entry Name: LEG7_HUMAN

NCBI Description

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]

Uniprot Description

LGALS7B: Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

Protein type: Cell adhesion; Apoptosis

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: extracellular space; cytoplasm; nucleus

Molecular Function: carbohydrate binding

Biological Process: heterophilic cell adhesion; apoptosis