Rabbit anti-Human LGALS3BP Polyclonal Antibody | anti-LGALS3BP antibody

LGALS3BP (M2BP, Galectin-3-binding protein, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding Protein, Tumor-associated antigen 90K) (Biotin)

Cat. Num. AAA6447528

• Gene Names: LGALS3BP; 90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B
• Reactivity: Human
• Applications: Immunohistochemistry, Immunofluorescence, Western Blot
• Purity: Purified by affinity chromatography.
• Synonyms: LGALS3BP; Polyclonal Antibody; LGALS3BP (M2BP; Galectin-3-binding protein; Lectin galactoside-binding soluble 3-binding protein; Mac-2-binding Protein; Tumor-associated antigen 90K) (Biotin); anti-LGALS3BP antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human LGALS3BP.
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-LGALS3BP antibody: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB)
• Application Notes: IHC: 1:50-1:200; IF: 1:50-1:100; WB: 1:500-1:2000; Applications are based on unconjugated antibody.
• Immunogen: Recombinant protein corresponding to human LGALS3BP.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Categories/Family for anti-LGALS3BP antibody

Antibodies; Lectins

NCBI and Uniprot Product Information

• NCBI GI #: 5031863
• NCBI GeneID: 3959
• NCBI Accession #: NP_005558.1
• NCBI GenBank Nucleotide #: NM_005567.3
• UniProt Accession #: Q08380; Q7M4S0; Q9UCH8; Q9UCH9; Q9UCI0
• Molecular Weight: 65,331 Da
• NCBI Official Full Name: galectin-3-binding protein
• NCBI Official Synonym Full Names: galectin 3 binding protein
• NCBI Official Symbol: LGALS3BP
• NCBI Official Synonym Symbols: 90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B
• NCBI Protein Information: galectin-3-binding protein
• UniProt Protein Name: Galectin-3-binding protein
• Protein Family: Galectin-3-binding protein
• UniProt Gene Name: LGALS3BP
• UniProt Synonym Gene Names: M2BP; MAC2BP; Mac-2 BP
• UniProt Entry Name: LG3BP_HUMAN

NCBI Description

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

Uniprot Description

LGALS3BP: Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: extracellular matrix; extracellular region; extracellular space; membrane; proteinaceous extracellular matrix

Molecular Function: scavenger receptor activity

Biological Process: cell adhesion; cellular defense response; platelet degranulation; receptor-mediated endocytosis; signal transduction