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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/25.)

Rabbit anti-Human LGALS3BP Polyclonal Antibody | anti-LGALS3BP antibody

LGALS3BP Antibody

Gene Names
LGALS3BP; 90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
LGALS3BP; Polyclonal Antibody; LGALS3BP Antibody; 90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B; anti-LGALS3BP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total LGALS3BP protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.3 mg/ml (varies by lot)
Sequence Length
585
Applicable Applications for anti-LGALS3BP antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:20-1:100
Immunogen Type
Protein
Immunogen Description
Fusion protein corresponding to residues near the C terminal of human lectin, galactoside-binding, soluble, 3 binding protein
Target Name
LGALS3BP
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/25.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/25.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue using at dilution 1/25.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue using at dilution 1/25.)
Related Product Information for anti-LGALS3BP antibody
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25.
Product Categories/Family for anti-LGALS3BP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
65,331 Da
NCBI Official Full Name
galectin-3-binding protein
NCBI Official Synonym Full Names
lectin, galactoside-binding, soluble, 3 binding protein
NCBI Official Symbol
LGALS3BP
NCBI Official Synonym Symbols
90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B
NCBI Protein Information
galectin-3-binding protein
UniProt Protein Name
Galectin-3-binding protein
UniProt Gene Name
LGALS3BP
UniProt Synonym Gene Names
M2BP; MAC2BP; Mac-2 BP
UniProt Entry Name
LG3BP_HUMAN

NCBI Description

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

Uniprot Description

LGALS3BP: Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; membrane

Molecular Function: scavenger receptor activity

Biological Process: receptor-mediated endocytosis; cellular defense response; cell adhesion; signal transduction

Research Articles on LGALS3BP

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Product Notes

The LGALS3BP lgals3bp (Catalog #AAA9410382) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LGALS3BP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LGALS3BP can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:20-1:100. Researchers should empirically determine the suitability of the LGALS3BP lgals3bp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LGALS3BP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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