Rabbit anti-Mouse LDLRAD3 Polyclonal Antibody | anti-LDLRAD3 antibody

LDLRAD3, CT (LDLRAD3, Low-density lipoprotein receptor class A domain-containing protein 3) (Azide free) (HRP)

Cat. Num. AAA6315661

• Gene Names: LDLRAD3; LRAD3
• Reactivity: Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LDLRAD3; Polyclonal Antibody; CT (LDLRAD3; Low-density lipoprotein receptor class A domain-containing protein 3) (Azide free) (HRP); Low-density lipoprotein receptor class A domain-containing protein 3; anti-LDLRAD3 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-LDLRAD3 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LDLRAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-345 amino acids from the C-terminal region of human LDLRAD3.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(LDLRAD3 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the LDLRAD3 antibody detected the LDLRAD3 protein (arrow).)

Related Product Information for anti-LDLRAD3 antibody

The specific function of the protein remains unknown.

Product Categories/Family for anti-LDLRAD3 antibody

Antibodies; Lipoproteins

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Kantojarvi, K., et al. Psychiatr. Genet. 20(3):102-108(2010).

NCBI and Uniprot Product Information

• NCBI GI #: 28557796
• NCBI GeneID: 143458
• NCBI Accession #: NP_777562.1
• NCBI GenBank Nucleotide #: NM_174902.2
• UniProt Accession #: Q86YD5; Q8NBJ0; B9EG81
• Molecular Weight: 37,419 Da
• NCBI Official Full Name: low-density lipoprotein receptor class A domain-containing protein 3
• NCBI Official Synonym Full Names: low density lipoprotein receptor class A domain containing 3
• NCBI Official Symbol: LDLRAD3
• NCBI Official Synonym Symbols: LRAD3
• NCBI Protein Information: low-density lipoprotein receptor class A domain-containing protein 3
• UniProt Protein Name: Low-density lipoprotein receptor class A domain-containing protein 3
• Protein Family: Low-density lipoprotein receptor class A domain-containing protein
• UniProt Gene Name: LDLRAD3
• UniProt Entry Name: LRAD3_HUMAN

Uniprot Description

LDLRAD3: May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. Belongs to the LDLR family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: plasma membrane; integral to membrane; cell junction

Molecular Function: beta-amyloid binding

Biological Process: receptor-mediated endocytosis