Western Blot (WB)
(Western blot analysis of 293T cell lysate using LDB1 Polyclonal Antibody at dilution of 1:1000)
Rabbit anti-Human, Mouse LDB1 Polyclonal Antibody | anti-LDB1 antibody
LDB1 Polyclonal Antibody
IHC: 1:70-1:350
ELISA: 1:5000-1:10000
Western Blot (WB)
(Western blot analysis of 293T cell lysate using LDB1 Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western blot analysis of 293T cell lysate using LDB1 Polyclonal Antibody at dilution of 1:1000)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using LDB1 Polyclonal Antibody at dilution of 1:70(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using LDB1 Polyclonal Antibody at dilution of 1:70(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using LDB1 Polyclonal Antibody at dilution of 1:70(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using LDB1 Polyclonal Antibody at dilution of 1:70(×200))
NCBI and Uniprot Product Information
Uniprot Description
LDB1: Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state. Belongs to the LDB family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 10q24-q25
Cellular Component: transcription factor complex; protein complex; nuclear chromatin; nucleus
Molecular Function: LIM domain binding; enzyme binding; protein homodimerization activity; protein self-association; chromatin binding; transcription corepressor activity
Biological Process: transcription from RNA polymerase II promoter; negative regulation of erythrocyte differentiation; positive regulation of cell adhesion; Wnt receptor signaling pathway; transcription, DNA-dependent; somatic stem cell maintenance; multicellular organismal development; gastrulation with mouth forming second; positive regulation of hemoglobin biosynthetic process; cellular component assembly; neuron differentiation; regulation of transcription, DNA-dependent; hair follicle development; cerebellar Purkinje cell differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; regulation of RNA elongation; anterior/posterior axis specification
Research Articles on LDB1
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Product Notes
The LDB1 ldb1 (Catalog #AAA2562823) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LDB1 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LDB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000-1:5000 IHC: 1:70-1:350 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the LDB1 ldb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LDB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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