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Western Blot (WB) (LCTL polyclonal antibody. Western Blot analysis of LCTL expression in human liver.)

Mouse anti-Human LCTL Polyclonal Antibody | anti-LCTL antibody

LCTL (KLPH, Lactase-like Protein, Klotho/Lactase-phlorizin Hydrolase-related Protein, FLJ33279, UNQ3022/PRO9820)

Gene Names
LCTL; KLG; KLPH
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
LCTL; Polyclonal Antibody; LCTL (KLPH; Lactase-like Protein; Klotho/Lactase-phlorizin Hydrolase-related Protein; FLJ33279; UNQ3022/PRO9820); Anti -LCTL (KLPH; anti-LCTL antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human LCTL.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MKPVWVATLLWMLLLVPRLGAARKGSPEEASFYYGTFPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQEDIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHWDLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHAPGLKLRGTGLYKAAHHIIKAHAKAWHSYNTTWRSKQQGLVGISLNCDWGEPVDISNPKDLEAAERYLQFCLGWFANPIYAGDYPQVMKDYIGRKSAEQGLEMSRLPVFSLQEKSYIKGTSDFLGLGHFTTRYITERNYPSRQGPSYQNDRDLIELVDPNWPDLGSKWLYSVPWGFRRLLNFAQTQYGDPPIYVMENGASQKFHCTQLCDEWRIQYLKGYINEMLKAIKDGANIKGYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRNKPRYPKASVQYYKKIIIANGFPNPREVESWYLKALETCSINNQMLAAEPLLSHMQMVTEIVVPTVCSLCVLITAVLLMLLLRRQS
Applicable Applications for anti-LCTL antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human LCTL, aa1-567 (AAI52991.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(LCTL polyclonal antibody. Western Blot analysis of LCTL expression in human liver.)

Western Blot (WB) (LCTL polyclonal antibody. Western Blot analysis of LCTL expression in human liver.)

Western Blot (WB)

(Western Blot analysis of LCTL expression in transfected 293T cell line by LCTL polyclonal antibody. Lane 1: LCTL transfected lysate (62.37kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of LCTL expression in transfected 293T cell line by LCTL polyclonal antibody. Lane 1: LCTL transfected lysate (62.37kD). Lane 2: Non-transfected lysate.)
Product Categories/Family for anti-LCTL antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
65,088 Da
NCBI Official Full Name
lactase-like protein isoform 1
NCBI Official Synonym Full Names
lactase-like
NCBI Official Symbol
LCTL
NCBI Official Synonym Symbols
KLG; KLPH
NCBI Protein Information
lactase-like protein; klotho gamma; KL lactase phlorizin hydrolase; klotho/lactase-phlorizin hydrolase-related protein
UniProt Protein Name
Lactase-like protein
Protein Family
UniProt Gene Name
LCTL
UniProt Synonym Gene Names
KLPH
UniProt Entry Name
LCTL_HUMAN

NCBI Description

This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Uniprot Description

Klotho gamma: Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q22.31

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds

Biological Process: carbohydrate metabolic process

Research Articles on LCTL

Similar Products

Product Notes

The LCTL lctl (Catalog #AAA6010801) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LCTL (KLPH, Lactase-like Protein, Klotho/Lactase-phlorizin Hydrolase-related Protein, FLJ33279, UNQ3022/PRO9820) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LCTL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the LCTL lctl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MKPVWVATLL WMLLLVPRLG AARKGSPEEA SFYYGTFPLG FSWGVGSSAY QTEGAWDQDG KGPSIWDVFT HSGKGKVLGN ETADVACDGY YKVQEDIILL RELHVNHYRF SLSWPRLLPT GIRAEQVNKK GIEFYSDLID ALLSSNITPI VTLHHWDLPQ LLQVKYGGWQ NVSMANYFRD YANLCFEAFG DRVKHWITFS DPRAMAEKGY ETGHHAPGLK LRGTGLYKAA HHIIKAHAKA WHSYNTTWRS KQQGLVGISL NCDWGEPVDI SNPKDLEAAE RYLQFCLGWF ANPIYAGDYP QVMKDYIGRK SAEQGLEMSR LPVFSLQEKS YIKGTSDFLG LGHFTTRYIT ERNYPSRQGP SYQNDRDLIE LVDPNWPDLG SKWLYSVPWG FRRLLNFAQT QYGDPPIYVM ENGASQKFHC TQLCDEWRIQ YLKGYINEML KAIKDGANIK GYTSWSLLDK FEWEKGYSDR YGFYYVEFND RNKPRYPKAS VQYYKKIIIA NGFPNPREVE SWYLKALETC SINNQMLAAE PLLSHMQMVT EIVVPTVCSL CVLITAVLLM LLLRRQS. It is sometimes possible for the material contained within the vial of "LCTL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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