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Rabbit anti-Human LCP1 Polyclonal Antibody | anti-LCP1 antibody

LCP1 (Center) Rabbit pAb

Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Synonyms
LCP1; Polyclonal Antibody; LCP1 (Center) Rabbit pAb; Plastin-2; L-plastin; LC64P; Lymphocyte cytosolic protein 1; LCP-1; PLS2; anti-LCP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Clone Number
RB39488
Purity/Purification
Affinity Purified
Form/Format
Supplied in PBS with 0.09% (W/V) Sodium Azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
627
Applicable Applications for anti-LCP1 antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Immunogen
This LCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-335 amino acids from the central region of human LCP1.
Cellular Localization
Cell Junction, Cell Membrane, Cell Projection, Cytoplasm, Cytoskeleton, Membrane

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
NCBI Official Full Name
lymphocyte cytosolic protein 1 (L-plastin), isoform CRA_a
UniProt Protein Name
Plastin-2
Protein Family
UniProt Gene Name
LCP1
UniProt Synonym Gene Names
PLS2; LCP-1
UniProt Entry Name
PLSL_HUMAN

Uniprot Description

L-plastin: Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Monomer. Interacts with AIF1. Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.

Protein type: Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 13q14.3

Cellular Component: ruffle; extracellular space; focal adhesion; cytoplasm; stress fiber; actin filament bundle; plasma membrane; actin filament; cytosol; filopodium; actin cytoskeleton; phagocytic cup

Molecular Function: actin filament binding; identical protein binding; calcium ion binding; actin binding

Biological Process: actin filament bundle formation; cell migration; organ regeneration; regulation of intracellular protein transport; T cell activation during immune response

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Product Notes

The LCP1 lcp1 (Catalog #AAA8553317) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LCP1 (Center) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LCP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the LCP1 lcp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LCP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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