Rabbit anti-Human LCN8 Polyclonal Antibody | anti-LCN8 antibody

LCN8, CT (LCN8, LCN5, Epididymal-specific lipocalin-8) (Biotin)

Cat. Num. AAA6315505

• Gene Names: LCN8; EP17; LCN5
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LCN8; Polyclonal Antibody; CT (LCN8; LCN5; Epididymal-specific lipocalin-8) (Biotin); Epididymal-specific lipocalin-8; anti-LCN8 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-LCN8 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LCN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-140 amino acids from the C-terminal region of human LCN8.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(LCN8 Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the LCN8 antibody detected the LCN8 protein (arrow).)

Related Product Information for anti-LCN8 antibody

Members of the lipocalin family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).

Product Categories/Family for anti-LCN8 antibody

Antibodies; Transport Proteins

References

Suzuki, K., et al. Gene 339, 49-59 (2004): Humphray, S.J., et al. Nature 429(6990):369-374(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 62988357
• NCBI GeneID: 138307
• NCBI Accession #: NP_848564.2
• NCBI GenBank Nucleotide #: NM_178469.3
• UniProt Accession #: Q6JVE9; Q5T5R4; A1L4A8; A6NMN9
• Molecular Weight: 17,254 Da
• NCBI Official Full Name: epididymal-specific lipocalin-8
• NCBI Official Synonym Full Names: lipocalin 8
• NCBI Official Symbol: LCN8
• NCBI Official Synonym Symbols: EP17; LCN5
• NCBI Protein Information: epididymal-specific lipocalin-8
• UniProt Protein Name: Epididymal-specific lipocalin-8
• Protein Family: Epididymal-specific lipocalin
• UniProt Gene Name: LCN8
• UniProt Synonym Gene Names: LCN5
• UniProt Entry Name: LCN8_HUMAN

NCBI Description

Members of the lipocalin family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]

Uniprot Description

LCN8: May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. Belongs to the calycin superfamily. Lipocalin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: extracellular region

Biological Process: transport; response to hormone stimulus